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The Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition
65) provides two mechanisms for administratively listing chemicals
which are known to the State to cause cancer or reproductive toxicity
(Health and Safety Code Section 25249.8(b)). One such mechanism
by which a chemical may be listed is if a body considered to be
authoritative by the state's qualified experts has formally identified
it as causing cancer or reproductive toxicity. The following are
identified as authoritative bodies for purposes of Proposition 65
as it pertains to chemicals known to cause cancer: the U.S. Environmental
Protection Agency, the International Agency for Research on Cancer,
the U.S. Food and Drug Administration, the National Institute for
Occupational Safety and Health, and the National Toxicology Program.
The criteria for listing chemicals through the authoritative bodies
mechanism are set forth in Title
22, California Code of Regulations (22 CCR), Section 12306.
As the lead agency for the implementation of Proposition 65, the
Office of Environmental Health Hazard Assessment (OEHHA) of the
California Environmental Protection Agency intends to list catechol
as known to the State to cause cancer, pursuant to this administrative
mechanism as provided in Health and Safety Code Section 25249.8(b)
and 22 CCR, Section 12306.
Relevant information on catechol (CAS No. 120-80-9) was
requested in a notice published in the California
Regulatory Notice Register
on September 29, 2000 (Register 00, No. 39-Z). A public forum
was held on October 26, 2000. OEHHA has determined that catechol
meets the criteria for listing under 22 CCR, Section 12306, and
therefore is issuing a notice of intent to list catechol under Proposition
65. A document providing more detail on the basis for the listing
of this chemical can be obtained from OEHHA's Proposition 65 Implementation
Office at the address and telephone number indicated below, or from
the OEHHA Web site at: http://www.oehha.ca.gov/
. Anyone objecting to the listing of catechol as causing cancer
on the basis that there is no substantial evidence that the criteria
for sufficiency of evidence as causing cancer specified in 22 CCR,
Section 12306 have been satisfied should provide written comments
in triplicate, along with supporting documentation, by mail or by
fax to:
Ms. Cynthia Oshita
Office of Environmental Health Hazard Assessment
Street Address: 1001 I Street
Sacramento, California 95814
Mailing Address: P.O. Box 4010
Sacramento, California 95812-4010
Fax No.: (916) 323-8803
Telephone: (916) 445-6900
Comments may also be hand-delivered to Ms. Oshita at the Office
of Environmental Health Hazard Assessment at the same address.
In order to be considered, comments must be postmarked (if sent
by mail) or received at OEHHA (if delivered in person or sent by
FAX) by 5:00 p.m. on Monday, June 16, 2003.
The following chemical has been determined by OEHHA to meet the
criteria set forth in 22 CCR, Section 12306 for listing as causing
cancer under the authoritative bodies mechanism:
| Chemical |
CAS No. |
Toxicological Endpoint |
Reference |
| Catechol |
120-80-9 |
Cancer |
IARC (1999) |
References
International Agency for Research on Cancer (IARC, 1999). IARC
Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume
71: 433-452. Re-evaluation of Some Organic Chemicals, Hydrazine
and Hydrogen Peroxide (Part Two). IARC, Lyon, France.
Follow this
link to download a copy of this notice.
Follow this
link to download a copy of the document providing more detail on
the basis for the listing of Catechol
You will need the free program Adobe Acrobat Reader to view or
print PDF files 
For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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