STATE OF CALIFORNIA
ENVIRONMENTAL PROTECTION
AGENCY
OFFICE OF ENVIRONMENTAL
HEALTH HAZARD ASSESSMENT
SAFE DRINKING WATER AND
TOXIC ENFORCEMENT ACT OF 1986
CHEMICALS KNOWN TO THE STATE
TO CAUSE CANCER OR REPRODUCTIVE TOXICITY
JANUARY 17, 2003
The Safe Drinking Water and Toxic Enforcement
Act of 1986 requires that the Governor revise and republish at least once per
year the list of chemicals known to the State to cause cancer or reproductive
toxicity. The identification number
indicated in the following list is the Chemical Abstracts Service (CAS)
Registry Number. No CAS number is given
when several substances are presented as a single listing. The date refers to the initial appearance of
the chemical on the list. For easy
reference, chemicals which are shown underlined are newly added. Chemicals which are shown with a strikeout
were placed on the list with the date noted, and have subsequently been
removed.
CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER
Chemical CAS
Number Date
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 26148685 January 1, 1990
Acetaldehyde 75070 April 1, 1988
Acetamide 60355 January 1, 1990
Acetochlor 34256821 January 1, 1989
2-Acetylaminofluorene 53963 July 1, 1987
Acifluorfen 62476599 January 1, 1990
Acrylamide 79061 January 1, 1990
Acrylonitrile 107131 July 1, 1987
Actinomycin D 50760 October 1, 1989
Adriamycin (Doxorubicin hydrochloride) 23214928 July 1, 1987
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide 3688537 July 1, 1987
Aflatoxins --- January 1, 1988
Alachlor 15972608 January 1, 1989
Alcoholic beverages, when associated with alcohol
abuse --- July 1, 1988
Aldrin 309002 July 1, 1988
Allyl chloride Delisted October 29, 1999 107051 January 1, 1990
2-Aminoanthraquinone 117793 October 1, 1989
p-Aminoazobenzene 60093 January 1, 1990
ortho-Aminoazotoluene 97563 July 1, 1987
4-Aminobiphenyl (4-aminodiphenyl) 92671 February 27, 1987
1-Amino-2,4-dibromoanthraquinone 81492 August 26, 1997
3-Amino-9-ethylcarbazole hydrochloride 6109973 July 1, 1989
2-Aminofluorene 153786 January 29, 1999
1-Amino-2-methylanthraquinone 82280 October 1, 1989
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 712685 July 1, 1987
4-Amino-2-nitrophenol 119346 January 29, 1999
Amitrole 61825 July 1, 1987
Analgesic mixtures containing phenacetin --- February 27, 1987
Aniline 62533 January 1, 1990
Aniline hydrochloride 142041 May 15, 1998
ortho-Anisidine 90040 July 1, 1987
ortho-Anisidine hydrochloride 134292 July 1, 1987
Antimony oxide (Antimony trioxide) 1309644 October 1, 1990
Aramite 140578 July 1, 1987
Arsenic (inorganic arsenic compounds) --- February 27, 1987
Asbestos 1332214 February 27, 1987
Auramine 492808 July 1, 1987
Azacitidine 320672 January 1, 1992
Azaserine 115026 July 1, 1987
Azathioprine 446866 February 27, 1987
Azobenzene 103333 January 1, 1990
Benz[a]anthracene 56553 July 1, 1987
Benzene 71432 February 27, 1987
Benzidine [and its salts] 92875 February 27, 1987
Benzidine-based dyes --- October 1, 1992
Benzo[b]fluoranthene 205992 July 1, 1987
Benzo[j]fluoranthene 205823 July 1, 1987
Benzo[k]fluoranthene 207089 July 1, 1987
Benzofuran 271896 October 1, 1990
Benzo[a]pyrene 50328 July 1, 1987
Benzotrichloride 98077 July 1, 1987
Benzyl chloride 100447 January 1, 1990
Benzyl violet 4B 1694093 July 1, 1987
Beryllium and beryllium compounds --- October 1, 1987
Betel quid with tobacco --- January 1, 1990
2,2-Bis(bromomethyl)-1,3-propanediol 3296900 May 1, 1996
Bis(2-chloroethyl)ether 111444 April 1, 1988
N,N-Bis(2-chloroethyl)-2-naphthylamine
(Chlornapazine) 494031 February 27, 1987
Bischloroethyl nitrosourea (BCNU) (Carmustine) 154938 July 1, 1987
Bis(chloromethyl)ether 542881 February 27, 1987
Bitumens, extracts of steam-refined and air refined --- January 1, 1990
Bracken fern --- January 1, 1990
Bromate 15541454 May 31, 2002
Bromodichloromethane 75274 January 1, 1990
Bromoform 75252 April 1, 1991
1,3-Butadiene 106990 April 1, 1988
1,4-Butanediol dimethanesulfonate (Busulfan) 55981 February 27, 1987
Butylated hydroxyanisole 25013165 January 1, 1990
beta-Butyrolactone 3068880 July 1, 1987
Cacodylic acid 75605 May 1, 1996
Cadmium and cadmium compounds --- October 1, 1987
Caffeic acid 331395 October 1, 1994
Captafol 2425061 October 1, 1988
Captan 133062 January 1, 1990
Carbazole 86748 May 1, 1996
Carbon tetrachloride 56235 October 1, 1987
Carbon-black extracts --- January 1, 1990
N-Carboxymethyl-N-nitrosourea 60391926 January 25, 2002
Ceramic fibers (airborne particles of respirable
size) --- July 1, 1990
Certain combined chemotherapy for lymphomas --- February 27, 1987
Chlorambucil 305033 February 27, 1987
Chloramphenicol 56757 October 1, 1989
Chlordane 57749 July 1, 1988
Chlordecone (Kepone) 143500 January 1, 1988
Chlordimeform 6164983 January 1, 1989
Chlorendic acid 115286 July 1, 1989
Chlorinated paraffins (Average chain length, C12; 108171262 July 1, 1989
approximately 60 percent chlorine by weight)
p-Chloroaniline 106478 October 1, 1994
p-Chloroaniline hydrochloride 20265967 May 15, 1998
Chlorodibromomethane Delisted October 29, 1999 124481 January
1, 1990
Chloroethane (Ethyl chloride) 75003 July 1, 1990
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) 13010474 January 1, 1988
(Lomustine)
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1- 13909096 October 1, 1988
nitrosourea (Methyl-CCNU)
Chloroform 67663 October 1, 1987
Chloromethyl methyl ether (technical grade) 107302 February 27, 1987
3-Chloro-2-methylpropene 563473 July 1, 1989
1-Chloro-4-nitrobenzene 100005 October 29, 1999
4-Chloro-ortho-phenylenediamine 95830 January 1, 1988
p-Chloro-o-toluidine 95692 January 1, 1990
p-Chloro-o-toluidine, strong acid salts of --- May 15, 1998
5-Chloro-o-toluidine and its strong acid salts --- October 24, 1997
Chloroprene 126998 June 2, 2000
Chlorothalonil 1897456 January 1, 1989
Chlorotrianisene 569573 September 1, 1996
Chlorozotocin 54749905 January 1, 1992
Chromium (hexavalent compounds) --- February 27, 1987
Chrysene 218019 January 1, 1990
C.I. Acid Red 114 6459945 July 1, 1992
C.I. Basic Red 9 monohydrochloride 569619 July 1, 1989
C.I.
Direct Blue 15 2429745 August 26, 1997
C.I.
Direct Blue 218 28407376 August 26, 1997
C.I. Solvent Yellow 14 842079 May 15, 1998
Ciclosporin (Cyclosporin A; Cyclosporine) 59865133 January 1, 1992
79217600
Cidofovir 113852372 January 29, 1999
Cinnamyl anthranilate 87296 July 1, 1989
Cisplatin 15663271 October 1, 1988
Citrus Red No. 2 6358538 October 1, 1989
Clofibrate 637070 September 1, 1996
Cobalt metal powder 7440484 July 1, 1992
Cobalt [II] oxide 1307966 July 1, 1992
Cobalt sulfate heptahydrate 10026241 June 2, 2000
Coke oven emissions --- February 27, 1987
Conjugated estrogens --- February 27, 1987
Creosotes --- October 1, 1988
para-Cresidine 120718 January 1, 1988
Cupferron 135206 January 1, 1988
Cycasin 14901087 January 1, 1988
Cyclophosphamide (anhydrous) 50180 February 27, 1987
Cyclophosphamide (hydrated) 6055192 February 27, 1987
Cytembena 21739913 May 15, 1998
D&C Orange No. 17 3468631 July 1, 1990
D&C Red No. 8 2092560 October 1, 1990
D&C Red No. 9 5160021 July 1, 1990
D&C Red No. 19 81889 July 1, 1990
Dacarbazine 4342034 January 1, 1988
Daminozide 1596845 January 1, 1990
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) 117102 January 1, 1992
Daunomycin 20830813 January 1, 1988
DDD
(Dichlorodiphenyldichloroethane) 72548 January 1, 1989
DDE
(Dichlorodiphenyldichloroethylene) 72559 January 1, 1989
DDT
(Dichlorodiphenyltrichloroethane) 50293 October 1, 1987
DDVP (Dichlorvos) 62737 January 1, 1989
N,N'-Diacetylbenzidine 613354 October 1, 1989
2,4-Diaminoanisole 615054 October 1, 1990
2,4-Diaminoanisole sulfate 39156417 January 1, 1988
4,4'-Diaminodiphenyl ether
(4,4'-Oxydianiline) 101804 January 1, 1988
2,4-Diaminotoluene 95807 January 1, 1988
Diaminotoluene (mixed) --- January 1, 1990
Dibenz[a,h]acridine 226368 January 1, 1988
Dibenz[a,j]acridine 224420 January 1, 1988
Dibenz[a,h]anthracene 53703 January 1, 1988
7H-Dibenzo[c,g]carbazole 194592 January 1, 1988
Dibenzo[a,e]pyrene 192654 January 1, 1988
Dibenzo[a,h]pyrene 189640 January 1, 1988
Dibenzo[a,i]pyrene 189559 January 1, 1988
Dibenzo[a,l]pyrene 191300 January 1, 1988
1,2-Dibromo-3-chloropropane
(DBCP) 96128 July 1, 1987
2,3-Dibromo-1-propanol 96139 October 1, 1994
Dichloroacetic acid 79436 May 1, 1996
p-Dichlorobenzene 106467 January 1, 1989
3,3'-Dichlorobenzidine 91941 October 1, 1987
3,3'-Dichlorobenzidine
dihydrochloride 612839 May 15, 1998
1,4-Dichloro-2-butene 764410 January 1, 1990
3,3'-Dichloro-4,4'-diaminodiphenyl
ether 28434868 January 1, 1988
1,1-Dichloroethane 75343 January 1, 1990
Dichloromethane (Methylene
chloride) 75092 April 1, 1988
1,2-Dichloropropane 78875 January 1, 1990
1,3-Dichloropropene 542756 January 1, 1989
Dieldrin 60571 July 1, 1988
Dienestrol 84173 January 1, 1990
Diepoxybutane 1464535 January 1, 1988
Diesel engine exhaust --- October 1, 1990
Di(2-ethylhexyl)phthalate 117817 January 1, 1988
1,2-Diethylhydrazine 1615801 January 1, 1988
Diethyl sulfate 64675 January 1, 1988
Diethylstilbestrol (DES) 56531 February 27, 1987
Diglycidyl resorcinol ether
(DGRE) 101906 July 1, 1989
Dihydrosafrole 94586 January 1, 1988
Diisopropyl sulfate 2973106 April 1, 1993
3,3'-Dimethoxybenzidine
(ortho-Dianisidine) 119904 January 1, 1988
3,3'-Dimethoxybenzidine
dihydrochloride 20325400 October 1, 1990
(ortho-Dianisidine dihydrochloride)
Dimethyl sulfate 77781 January 1, 1988
4-Dimethylaminoazobenzene 60117 January 1, 1988
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2- 55738540 January 1, 1988
furyl)vinyl]-1,3,4-oxadiazole
7,12-Dimethylbenz(a)anthracene 57976 January 1, 1990
3,3'-Dimethylbenzidine (ortho-Tolidine) 119937 January 1, 1988
3,3'-Dimethylbenzidine
dihydrochloride 612828 April 1, 1992
Dimethylcarbamoyl chloride 79447 January 1, 1988
1,1-Dimethylhydrazine (UDMH) 57147 October 1, 1989
1,2-Dimethylhydrazine 540738 January 1, 1988
Dimethylvinylchloride 513371 July 1, 1989
3,7-Dinitrofluoranthene 105735715 August 26, 1997
3,9-Dinitrofluoranthene 22506532 August 26, 1997
1,6-Dinitropyrene 42397648 October 1, 1990
1,8-Dinitropyrene 42397659 October 1, 1990
Dinitrotoluene mixture, 2,4-/2,6- --- May 1, 1996
2,4-Dinitrotoluene 121142 July 1, 1988
2,6-Dinitrotoluene 606202 July 1, 1995
Di-n-propyl isocinchomeronate (MGK Repellent 326) 136458 May 1, 1996
1,4-Dioxane 123911 January 1, 1988
Diphenylhydantoin (Phenytoin) 57410 January 1, 1988
Diphenylhydantoin (Phenytoin), sodium salt 630933 January 1, 1988
Direct Black 38 (technical grade) 1937377 January 1, 1988
Direct Blue 6 (technical grade) 2602462 January 1, 1988
Direct Brown 95 (technical grade) 16071866 October 1, 1988
Disperse Blue 1 2475458 October 1, 1990
Diuron 330541 May 31, 2002
Epichlorohydrin 106898 October 1, 1987
Erionite 12510428 October 1, 1988
Estradiol 17B 50282 January 1, 1988
Estrone 53167 January 1, 1988
Estropipate 7280377 August 26, 1997
Ethinylestradiol 57636 January 1, 1988
Ethoprop 13194484 February 27, 2001
Ethyl acrylate 140885 July 1, 1989
Ethyl methanesulfonate 62500 January 1, 1988
Ethyl-4,4'-dichlorobenzilate 510156 January 1, 1990
Ethylene dibromide 106934 July 1, 1987
Ethylene dichloride (1,2-Dichloroethane) 107062 October 1, 1987
Ethylene oxide 75218 July 1, 1987
Ethylene thiourea 96457 January 1, 1988
Ethyleneimine 151564 January 1, 1988
Fenoxycarb 72490018 June 2, 2000
Folpet 133073 January 1, 1989
Formaldehyde (gas) 50000 January 1, 1988
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole 3570750 January 1, 1988
Furan 110009 October 1, 1993
Furazolidone 67458 January 1, 1990
Furmecyclox 60568050 January 1, 1990
Fusarin C 79748815 July 1, 1995
Ganciclovir
sodium 82410320 August 26, 1997
Gasoline engine exhaust (condensates/extracts) --- October 1, 1990
Glasswool fibers (airborne particles of respirable
size) --- July 1, 1990
Glu-P-1 (2-Amino-6-methyldipyrido[1,2- 67730114 January 1, 1990
a:3',2'-d]imidazole)
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) 67730103 January 1, 1990
Glycidaldehyde 765344 January 1, 1988
Glycidol 556525 July 1, 1990
Griseofulvin 126078 January 1, 1990
Gyromitrin (Acetaldehyde methylformylhydrazone) 16568028 January 1, 1988
HC Blue 1 2784943 July 1, 1989
Heptachlor 76448 July 1, 1988
Heptachlor epoxide 1024573 July 1, 1988
Hexachlorobenzene 118741 October 1, 1987
Hexachlorocyclohexane (technical grade) --- October 1, 1987
Hexachlorodibenzodioxin 34465468 April 1, 1988
Hexachloroethane 67721 July 1, 1990
Hexamethylphosphoramide 680319 January 1, 1988
Hydrazine 302012 January 1, 1988
Hydrazine sulfate 10034932 January 1, 1988
Hydrazobenzene (1,2-Diphenylhydrazine) 122667 January 1, 1988
Indeno [1,2,3-cd]pyrene 193395 January 1, 1988
IQ (2-Amino-3-methylimidazo[4,5-f]quinoline) 76180966 April 1, 1990
Iprodione 36734197 May 1, 1996
Iron dextran complex 9004664 January 1, 1988
Isobutyl nitrite 542563 May 1, 1996
Isoprene 78795 May 1, 1996
Isosafrole 120581 October 1, 1989
Lactofen 77501634 January 1, 1989
Lasiocarpine 303344 April 1, 1988
Lead acetate 301042 January 1, 1988
Lead and lead compounds --- October 1, 1992