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Chemicals Listed Effective December 19, 2008 As Known To The State Of California To Cause Cancer Or Reproductive Toxicity: 2,4,6-Trinitrotoluene (TNT) (CAS No. 118-96-7) and Chromium (hexavalent compounds)
[12/18/08]

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is adding two chemicals to the list of chemicals known to the State to cause cancer or reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 651).  The chemicals are 2,4,6-Trinitrotoluene (TNT) (CAS No. 118-96-7) and Chromium (hexavalent compounds).  2,4,6-Trinitrotoluene (TNT) and Chromium (hexavalent compounds) are listed effective December 19, 2008. 

2,4,6-Trinitrotoluene (TNT) (CAS No. 118-96-7) was considered by the “state’s qualified experts” (the Carcinogen Identification Committee (CIC) of the OEHHA Science Advisory Board2) at a public meeting held on November 5, 2008.  The CIC determined that 2,4,6-trinitrotoluene (TNT) (CAS No. 118-96-7) was clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer.  Regulations governing the criteria for listing of chemicals by the “state’s qualified experts” (Carcinogen Identification Committee) mechanism are set out in Title 27, California Code of Regulations, section 25305(a)(1) (formerly Title 22, California Code of Regulations, section 12305(a)(1)). 

Chromium (hexavalent compounds) was considered by the Developmental and Reproductive Toxicant (DART) Identification Committee of the OEHHA Science Advisory Board3) at a public meeting held on November 20, 2008.  The DART Identification Committee determined that chromium (hexavalent compounds) was clearly shown, through scientifically valid testing according to generally accepted principles, to cause reproductive toxicity (including all endpoints, developmental toxicity, male reproductive toxicity and female reproductive toxicity).  Regulations governing the criteria for listing of chemicals by the “state’s qualified experts” (DART Identification Committee) mechanism are set out in Title 27, California Code of Regulations, section 25305(b)(1) (formerly Title 22, California Code of Regulations, section 12305(b)(1)).

A complete, updated chemical list is available for download at the links below.

In summary, the following chemicals are being listed under Proposition 65 as known to the State to cause: 

Cancer

2,4,6-Trinitrotoluene (TNT) Listed as a Carcinogen
Chemical CAS No Toxicological Endpoint Listing Mechanism4

Listing mechanism:  SQE – “state’s qualified experts” mechanism (27 CCR section 25305(a)(1)).

2,4,6-Trinitrotoluene (TNT) 118-96-7
Cancer
SQE

Reproductive Toxicity

Chemical CAS No Toxicological Endpoint Listing Mechanism5
Chromium (hexavalent compounds)   Developmental toxicity Female reproductive toxicity Male reproductive toxicity
SQE

A complete, updated Proposition 65 list is available for download as a pdf file here.

If you would like to sort the list by CAS number or date, please download the list as a Excel, hyphenated and with the associated Safe Harbor Levels here. You can then sort the list by date, CAS number or chemical name using MS Excel.

 

1 Health and Safety Code section 25249.5 et seq.

2 Health and Safety Code section 25249.8(b) and Title 27, Cal Code of Regs., section 25302 et seq.

3 Health and Safety Code section 25249.8(b) and Title 27, Cal Code of Regs., section 25302 et seq.

4 Listing mechanism:  SQE – “state’s qualified experts” mechanism (27 CCR section 25305(a)(1)).

5 Listing mechanism:  SQE – “state’s qualified experts” mechanism (27 CCR section 25305(b)(1)).

 
 
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