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The Office of Environmental Health Hazard Assessment
(OEHHA) of the California Environmental Protection Agency is adding
five chemicals to the list of chemicals known to the State to
cause cancer or reproductive toxicity for purposes of the Safe
Drinking Water and Toxic Enforcement Act of 1986 (Proposition
65). The chemicals are listed effective December 22, 2000.
Bromoethane and isoxaflutole are listed pursuant
to an administrative listing mechanism provided under Proposition
65, based upon a formal identification by an authoritative body
that the chemicals cause cancer. Regulations governing the listing
of chemicals under the "authoritative bodies" mechanism
are published in Title 22, California Code of Regulations, Section
12306 (22 CCR 12306).
Gemfibrozil is listed as a chemical known to the
State to cause cancer and zileuton is listed as a chemical known
to the State to cause cancer, developmental toxicity and female
reproductive toxicity. The listing of these chemicals is based
on a formal requirement by a state or federal agency that the
chemical be identified or labeled as causing cancer or reproductive
toxicity pursuant to an administrative listing mechanism provided
under the Act. Regulations governing the listing of chemicals
under the "formally required to be labeled or identified"
mechanism are published in Title 22, California Code of Regulations,
Section 12902.
The reader is directed to the Notice of Intent to
List Chemicals published in the August
25, 2000 issue of the California Regulatory Notice Register
(Register 00, No. 34-Z) for the supporting documentation for the
chemicals bromoethane, gemfibrozil, isoxaflutole and zileuton
which OEHHA relied upon in making its determination that the criteria
for administrative listing had been satisfied.
MX (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone)
is listed as causing cancer based upon a determination made by
the "state's qualified experts" (the Carcinogen Identification
Committee) at a public meeting that it has been clearly shown,
through scientifically valid testing according to generally accepted
principles, to cause cancer. Regulations governing the listing
of chemicals by the "state's qualified experts" mechanism
are published in Title 22, California Code of Regulations, Section
12305(a)(1).
The reader is directed to the Notice to Interested
Parties published in the August
25, 2000 issue of the California Regulatory Notice Register
(Register 00, No. 34-Z) for the supporting documentation which
the Committee relied upon in making its determination that the
criteria for listing have been satisfied.
A complete, updated chemical list is published elsewhere
in this issue of the California Regulatory Notice Register.
The five chemicals listed, effective December 22,
2000, and the mechanism under which each is listed, are shown
below:
Chemicals Known to the State to Cause Cancer:
| Chemical |
CAS No. |
Listing Mechanism1 |
|
Bromoethane
Gemfibrozil
Isoxaflutole
MX (3-chloro-4-(dichloromethyl) -5-hydroxy-2(5H)-furanone)
Zileuton
|
74-96-4
25812-30-0
141112-29-0
77439-76-0
11406-87-2
|
AB
FR
AB
SQE
FR
|
Chemical Known to the State to Cause Reproductive
Toxicity:
| Chemical |
CAS No. |
Endpoint |
Listing Mechanism1 |
|
Zileuton
|
111406-87-2
|
Developmental toxicity
Female reproductive toxicity |
FR
|
1Listing mechanism:
AB - "authoritative bodies" mechanism
(22 CCR 12306)
FR - "formally required to be labeled or identified"
mechanism (22 CCR12902)
SQE - "state's qualified experts" mechanism
(22 CCR 12305 (a)(1))
Download the December 22,
2000 Proposition 65 List:
View the December 22, 2000 Proposition 65 List.
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