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Proposition 65

Results of First Round Pilot Random Selection of Chemicals Eligible for Prioritization for Consideration of Carcinogenicity Evaluation
[08/05/97]

Table 1

NO.

NAME
(ALPHABETICAL ORDER) 

CAS NUMBER

REMARKS    

1. acetoxymethyl-phenylnitrosamine 81943-37-5 chemical research
2. acronycine 7008-42-6 evaluated but not approved as anti-neoplastic drug
3. allyl isothiocyanate 57-06-7 dog and cat repellent, flavoring
4. allyl isovalerate 2835-39-4 fragrance in cosmetics, flavoring agent
5. amino-2-nitrophenol, 4- 119-34-6  dye for furs, etching printing plates
6. amino-4-ethoxyacetanilide, 3- 17026-81-2 intermediate for synthesis of dyes
7. amino-5-(5-nitro-2-furyl)-1,3,4-oxadiazole, 2 3775-55-1 evaluated but not approved as an anti-microbial drug
8. amino-5-nitrothiazole, 2- 121-66-4 antiprotozoan drug for chickens
9. aminofluorene, 2- 153-78-6 chemical research
10. aminoundecanoic acid, 11- 2432-99-7 initiator in nylon synthesis
11. atrazine 1912-24-9 herbicide with extensive use
12. benzoquinone dioxime, p- {quinone dioxime, p-} 105-11-3 accelerator in rubber manufacture
13. biphenylamine hydrochloride, 2- {aminobiphenyl hydrochloride, 2-} 2185-92-4 intermediate in chemical synthesis
14. bis(2-chloro-1-methylethyl) ether 108-60-1 solvent and chemical intermediate
15. bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)-quinazoline, 4- 33372-39-3 evaluated but not approved as an anti-helminthic drug
16. bis(tri-N-butyltin)oxide 56-35-9 in antifouling marine paints, wood and textile preservative
17. bromoethane (ethyl bromide) 74-96-4 extensively used soil and structure fumigant 
18. butyl bromide, tert- 507-19-7 intermediate for chemical synthesis
19. butyl-N-nitrosourea, N- 869-01-2 not produced commercially, used in chemical/biological research 
20. C.I. acid blue 9 and its salts 2650-18-2 dye for nylon, wool, etc.
21. C.I. acid orange 3 6373-74-6 dye for nylon, wool, etc.
22. C.I. acid red 51 16423-68-0 food dye
23. C.I. solvent yellow 14 (sudan 1) 842-07-9 dye for oils, solvents, waxes, shoe polish, plastic
24. C.I. vat yellow 4 128-66-5 dye for cotton, silk, wool, paper
25. Carbamazepine 298-46-4  anticonvulsant and analgesic drug 
26. chlorinated paraffins (C23; 43% chlorine) 108171-27-3 waxes
27. chloro-4'-aminodiphenylether, 4- 101-79-1 additive to lubricants, flame retardants in rubber
28. chloro-m-phenylenediamine, 4- 5131-60-2 chemical research
29. chloromethane (methyl chloride) 74-87-3 extensively used for silicone rubber synthesis
30. chloromethylpyridine hydrochloride, 3- 6959-48-4 research chemical
31. chloronitrobenzene, p- 100-00-5 intermediate for chemical synthesis
32. chlorthal-dimethyl (DCPA) 1861-32-1 selective herbicide
33. chromium picolinate 000-00-3 source of essential chromium
34. chrysoidine (C.I. solvent orange 3) 532-82-1 dye for silk, cotton, oils, waxes
35. cresidine, m- 102-50-1 no commercial use in 1982 (IARC)
36. cyanazine 21725-46-2 herbicide
37. cytembena 21739-91-3 evaluated but not approved as anti-neoplastic drug
38. D&C yellow no. 11 (C.I. solvent yellow 33) 8003-22-3 pigment and dye
39. dapsone (sulfonyldianiline, 4,4'-) 80-08-0 pharmaceutical for treatment of leprosy, previous candidate for an authoritative bodies listing 
40. di(2-ethylhexyl)adipate 103-23-1 plasticizer, solvent in certain cosmetics
41. diallate 2303-16-4 selective herbicide
42. dibromomannitol 488-41-5 evaluated but not approved as anti-neoplastic drug
43. dichlorophenoxyacetic acid, 2,4-(including salts & esters) (2,4- D) 94-75-7 extensively used broad-leaf herbicide
44. dicofol 115-32-2 extensively used pesticide for mite control
45. diethylthiourea, N,N'- 105-55-5 accelerator for rubber production
46. diftalone 21626-89-1 evaluated but not approved as anti-inflammatory drug
47. dimethoxy-4'-aminostilbene, 2,5- 23435-31-6 intermediate in chemical synthesis
48. dimethoxybenzidine-4,4'-diisocyanate,3,3'- 91-93-0 not produced commercially in 1977
49. dimethyl hydrogen phosphite 868-85-9 lubricant additive
50. dimethyldiazene-1-oxide (methylazoxymethane/ azoxymethane) 25843-45-2 chemical/biological research
51. estradiol mustard 22966-79-6 evaluated but not approved as anti-neoplastic drug
52. estragole [1-methoxy-4-(2-propenyl)benzene]     140-67-0 flavoring agent in food, fragrance in cosmetics
53. ethyl-N-formylhydrazine, N- 74920-78-8 research chemical
54. FD&C blue no. 2 860-22-0 food coloring
55. FD&C green no. 1 (guinea green) 4680-78-8 dye for wool, silk, leather, paper; cosmetic pigment
56. furfural 98-01-1 extensive use as solvent, in adhesives, as a flavoring, in chemical synthesis
57. ICRF-159 21416-87-5 experimental drug (not approved)
58. isophosphamide (ifosfamide) 3778-73-2 anti-neoplastic drug
59. malathion 121-75-5 insecticide
60. malonaldehyde, sodium salt 24382-04-5 produced by metabolism in the human body
61. methyl carbamate 598-55-0 chemical intermediate for resin and drug synthesis
62. methyl methacrylate 80-62-6 widely used for polymer synthesis
63. mexacarbate (zectran) 315-18-4 pesticide for control of insects and mites
64. molybdenum trioxide 1313-27-5 used in alloys and as catalyst
65. nalidixic acid 389-08-2 drug for urinary tract infections: proposed for listing via authoritative bodies
66. naphthalenediamine, 1,5- 2243-62-1 chemical intermediate
67. nithiazide 139-94-6 used as antiprotozoan drug in poultry (IARC) 
68. nitrobenzimidazole, 6- 94-52-0 used in photographic developers 
69. omeprazole 73590-58-6 antacid drug
70. patulin 149-29-1 mycotoxin not produced or used commercially
71. pentachloronitrobenzene (PCNB) 82-68-8 fungicide for soil, lawns, and food crops
72. petasitenine 60102-37-6 used in folk medicine, herbal medicine
73. phenelzine sulfate 156-51-4 antidepressant drug
74. piperonyl sulfoxide 120-62-7 insecticide synergism
75. pivalolactone 1955-45-9 intermediate in chemical synthesis
76. ritalin (methylphenidate) and its hydrochloride 113-45-1 drug for treatment of hyperactive children
77. salicylazosulfapyridine 599-79-1 drug for treatment of inflammatory bowel d
78. simazine 122-34-9 herbicide 
79. tetrachlorvinphos 22248-79-9 insecticide
80. thioguanine deoxyriboside, beta- 789-61-7 evaluated but not approved as anti-neoplastic drug
81. trichloroacetic acid 76-03-9 herbicide, soil stimulant, intermediate for chemical synthesis
82. trimethylaniline, 2,4,6- & its hydrochloride (aminomesitylene) 88-05-1 intermediate for chemical synthesis
83. trimethylthiourea   2489-77-2 accelerator for rubber production and curing agent 
84. zearalenone 17924-92-4 intermediate for chemical synthesis
85. ziram 137-30-4 accelerator for rubber production, fungicide on food crops, snail control

 

 
 
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