STATE OF CALIFORNIA
ENVIRONMENTAL PROTECTION
AGENCY
OFFICE OF ENVIRONMENTAL
HEALTH HAZARD ASSESSMENT
SAFE DRINKING WATER AND
TOXIC ENFORCEMENT ACT OF 1986
CHEMICALS KNOWN TO THE STATE
TO CAUSE CANCER OR REPRODUCTIVE TOXICITY
NOVEMBER 14, 2003
The Safe Drinking Water and Toxic Enforcement
Act of 1986 requires that the Governor revise and republish at least once per
year the list of chemicals known to the State to cause cancer or reproductive
toxicity. The identification number
indicated in the following list is the Chemical Abstracts Service (CAS)
Registry Number. No CAS number is given
when several substances are presented as a single listing. The date refers to the initial appearance of
the chemical on the list. For easy
reference, chemicals which are shown underlined are newly added. Chemicals which are shown with a strikeout
were placed on the list with the date noted, and have subsequently been
removed.
CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER
|
Chemical |
CAS Number |
Date |
|
|
|
|
|
A-alpha-C
(2-Amino-9H-pyrido[2,3-b]indole) |
26148685 |
January 1, 1990 |
|
Acetaldehyde |
75070 |
April 1, 1988 |
|
Acetamide |
60355 |
January 1, 1990 |
|
Acetochlor |
34256821 |
January 1, 1989 |
|
2-Acetylaminofluorene |
53963 |
July 1, 1987 |
|
Acifluorfen |
62476599 |
January 1, 1990 |
|
Acrylamide |
79061 |
January 1, 1990 |
|
Acrylonitrile |
107131 |
July 1, 1987 |
|
Actinomycin D |
50760 |
October 1, 1989 |
|
Adriamycin (Doxorubicin
hydrochloride) |
23214928 |
July 1, 1987 |
|
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide |
3688537 |
July 1, 1987 |
|
Aflatoxins |
--- |
January 1, 1988 |
|
Alachlor |
15972608 |
January 1, 1989 |
|
Alcoholic beverages, when
associated with alcohol abuse |
--- |
July 1, 1988 |
|
Aldrin |
309002 |
July 1, 1988 |
|
|
|
|
|
2-Aminoanthraquinone |
117793 |
October 1, 1989 |
|
p-Aminoazobenzene |
60093 |
January 1, 1990 |
|
ortho-Aminoazotoluene |
97563 |
July 1, 1987 |
|
4-Aminobiphenyl (4-aminodiphenyl) |
92671 |
February 27, 1987 |
|
1-Amino-2,4-dibromoanthraquinone |
81492 |
August 26, 1997 |
|
3-Amino-9-ethylcarbazole
hydrochloride |
6109973 |
July 1, 1989 |
|
2-Aminofluorene |
153786 |
January 29, 1999 |
|
1-Amino-2-methylanthraquinone |
82280 |
October 1, 1989 |
|
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole |
712685 |
July 1, 1987 |
|
4-Amino-2-nitrophenol |
119346 |
January 29, 1999 |
|
Amitrole |
61825 |
July 1, 1987 |
|
Analgesic mixtures containing
phenacetin |
--- |
February 27, 1987 |
|
Aniline |
62533 |
January 1, 1990 |
|
Aniline hydrochloride |
142041 |
May 15, 1998 |
|
ortho-Anisidine |
90040 |
July 1, 1987 |
|
ortho-Anisidine
hydrochloride |
134292 |
July 1, 1987 |
|
Antimony oxide (Antimony
trioxide) |
1309644 |
October 1, 1990 |
|
Aramite |
140578 |
July 1, 1987 |
|
Arsenic (inorganic arsenic
compounds) |
--- |
February 27, 1987 |
|
Asbestos |
1332214 |
February 27, 1987 |
|
Auramine |
492808 |
July 1, 1987 |
|
Azacitidine |
320672 |
January 1, 1992 |
|
Azaserine |
115026 |
July 1, 1987 |
|
Azathioprine |
446866 |
February 27, 1987 |
|
Azobenzene |
103333 |
January 1, 1990 |
|
|
|
|
|
Benz[a]anthracene |
56553 |
July 1, 1987 |
|
Benzene |
71432 |
February 27, 1987 |
|
Benzidine [and its salts] |
92875 |
February 27, 1987 |
|
Benzidine-based dyes |
--- |
October 1, 1992 |
|
Benzo[b]fluoranthene |
205992 |
July 1, 1987 |
|
Benzo[j]fluoranthene |
205823 |
July 1, 1987 |
|
Benzo[k]fluoranthene |
207089 |
July 1, 1987 |
|
Benzofuran |
271896 |
October 1, 1990 |
|
Benzo[a]pyrene |
50328 |
July 1, 1987 |
|
Benzotrichloride |
98077 |
July 1, 1987 |
|
Benzyl chloride |
100447 |
January 1, 1990 |
|
Benzyl violet 4B |
1694093 |
July 1, 1987 |
|
Beryllium and beryllium
compounds |
--- |
October 1, 1987 |
|
Betel quid with tobacco |
--- |
January 1, 1990 |
|
2,2-Bis(bromomethyl)-1,3-propanediol |
3296900 |
May 1, 1996 |
|
Bis(2-chloroethyl)ether |
111444 |
April 1, 1988 |
|
N,N-Bis(2-chloroethyl)-2-naphthylamine
(Chlornapazine) |
494031 |
February 27, 1987 |
|
Bischloroethyl nitrosourea
(BCNU) (Carmustine) |
154938 |
July 1, 1987 |
|
Bis(chloromethyl)ether |
542881 |
February 27, 1987 |
Bis(2-chloro-1-methylethyl)ether,
technical grade
|
---
|
October
29, 1999
|
|
Bitumens, extracts of
steam-refined and air refined |
--- |
January 1, 1990 |
|
Bracken fern |
--- |
January 1, 1990 |
|
Bromate |
15541454 |
May 31, 2002 |
|
Bromodichloromethane |
75274 |
January 1, 1990 |
Bromoethane
|
74964
|
December
22, 2000
|
|
Bromoform |
75252 |
April 1, 1991 |
|
1,3-Butadiene |
106990 |
April 1, 1988 |
|
1,4-Butanediol
dimethanesulfonate (Busulfan) |
55981 |
February 27, 1987 |
|
Butylated hydroxyanisole |
25013165 |
January 1, 1990 |
|
beta-Butyrolactone |
3068880 |
July 1, 1987 |
|
|
|
|
|
Cacodylic acid |
75605 |
May 1, 1996 |
|
Cadmium and cadmium
compounds |
--- |
October 1, 1987 |
|
Caffeic
acid |
331395 |
October
1, 1994 |
|
Captafol |
2425061 |
October 1, 1988 |
|
Captan |
133062 |
January 1, 1990 |
|
Carbazole |
86748 |
May 1, 1996 |
|
Carbon black (airborne,
unbound particles of respirable size) |
1333864 |
February 21, 2003 |
|
Carbon tetrachloride |
56235 |
October 1, 1987 |
|
Carbon-black extracts |
--- |
January 1, 1990 |
|
N-Carboxymethyl-N-nitrosourea |
60391926 |
January 25, 2002 |
Catechol
|
120809 |
July 15, 2003 |
|
Ceramic fibers (airborne
particles of respirable size) |
--- |
July 1, 1990 |
|
Certain combined
chemotherapy for lymphomas |
--- |
February 27, 1987 |
|
Chlorambucil |
305033 |
February 27, 1987 |
|
Chloramphenicol |
56757 |
October 1, 1989 |
|
Chlordane |
57749 |
July 1, 1988 |
|
Chlordecone (Kepone) |
143500 |
January 1, 1988 |
|
Chlordimeform |
6164983 |
January 1, 1989 |
|
Chlorendic acid |
115286 |
July 1, 1989 |
|
Chlorinated paraffins (Average chain length, C12; approximately 60 percent chlorine by weight) |
108171262 |
July 1, 1989 |
|
p-Chloroaniline |
106478 |
October 1, 1994 |
|
p-Chloroaniline
hydrochloride |
20265967 |
May 15, 1998 |
|
|
|
|
|
Chloroethane (Ethyl
chloride) |
75003 |
July 1, 1990 |
|
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
(CCNU) (Lomustine) |
13010474 |
January 1, 1988 |
|
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-
nitrosourea (Methyl-CCNU) |
13909096 |
October 1, 1988 |
|
Chloroform |
67663 |
October 1, 1987 |
|
Chloromethyl methyl ether
(technical grade) |
107302 |
February 27, 1987 |
|
3-Chloro-2-methylpropene |
563473 |
July 1, 1989 |
|
1-Chloro-4-nitrobenzene |
100005 |
October 29, 1999 |
|
4-Chloro-ortho-phenylenediamine |
95830 |
January 1, 1988 |
|
p-Chloro-o-toluidine |
95692 |
January 1, 1990 |
|
p-Chloro-o-toluidine,
strong acid salts of |
--- |
May 15, 1998 |
|
5-Chloro-o-toluidine and
its strong acid salts |
--- |
October 24, 1997 |
|
Chloroprene |
126998 |
June 2, 2000 |
|
Chlorothalonil |
1897456 |
January 1, 1989 |
|
Chlorotrianisene |
569573 |
September 1, 1996 |
|
Chlorozotocin |
54749905 |
January 1, 1992 |
|
Chromium (hexavalent
compounds) |
--- |
February 27, 1987 |
|
Chrysene |
218019 |
January 1, 1990 |
|
C.I. Acid Red 114 |
6459945 |
July 1, 1992 |
|
C.I. Basic Red 9
monohydrochloride |
569619 |
July 1, 1989 |
|
C.I. Direct Blue 15 |
2429745 |
August 26, 1997 |
|
C.I. Direct Blue 218 |
28407376 |
August 26, 1997 |
|
C.I. Solvent Yellow 14 |
842079 |
May 15, 1998 |
|
Ciclosporin (Cyclosporin
A; Cyclosporine) |
59865133, 79217600 |
January 1, 1992 |
|
|
|
|
|
Cidofovir |
113852372 |
January 29, 1999 |
|
Cinnamyl anthranilate |
87296 |
July 1, 1989 |
|
Cisplatin |
15663271 |
October 1, 1988 |
|
Citrus Red No. 2 |
6358538 |
October 1, 1989 |
|
Clofibrate |
637070 |
September 1, 1996 |
|
Cobalt metal powder |
7440484 |
July 1, 1992 |
|
Cobalt [II] oxide |
1307966 |
July 1, 1992 |
|
Cobalt sulfate
heptahydrate |
10026241 |
June 2, 2000 |
|
Coke oven emissions |
--- |
February 27, 1987 |
|
Conjugated estrogens |
--- |
February 27, 1987 |
|
Creosotes |
--- |
October 1, 1988 |
|
para-Cresidine |
120718 |
January 1, 1988 |
|
Cupferron |
135206 |
January 1, 1988 |
|
Cycasin |
14901087 |
January 1, 1988 |
|
Cyclophosphamide
(anhydrous) |
50180 |
February 27, 1987 |
|
Cyclophosphamide
(hydrated) |
6055192 |
February 27, 1987 |
|
Cytembena |
21739913 |
May 15, 1998 |
|
|
|
|
|
D&C Orange No. 17 |
3468631 |
July 1, 1990 |
|
D&C Red No. 8 |
2092560 |
October 1, 1990 |
|
D&C Red No. 9 |
5160021 |
July 1, 1990 |
|
D&C Red No. 19 |
81889 |
July 1, 1990 |
|
Dacarbazine |
4342034 |
January 1, 1988 |
|
Daminozide |
1596845 |
January 1, 1990 |
|
Dantron (Chrysazin;
1,8-Dihydroxyanthraquinone) |
117102 |
January 1, 1992 |
|
Daunomycin |
20830813 |
January 1, 1988 |
|
DDD (Dichlorodiphenyldichloroethane) |
72548 |
January 1, 1989 |
|
DDE
(Dichlorodiphenyldichloroethylene) |
72559 |
January 1, 1989 |
|
DDT
(Dichlorodiphenyltrichloroethane) |
50293 |
October 1, 1987 |
|
DDVP (Dichlorvos) |
62737 |
January 1, 1989 |
|
N,N'-Diacetylbenzidine |
613354 |
October 1, 1989 |
|
2,4-Diaminoanisole |
615054 |
October 1, 1990 |
|
2,4-Diaminoanisole sulfate |
39156417 |
January 1, 1988 |
|
4,4'-Diaminodiphenyl ether
(4,4'-Oxydianiline) |
101804 |
January 1, 1988 |
|
2,4-Diaminotoluene |
95807 |
January 1, 1988 |
|
Diaminotoluene (mixed) |
--- |
January 1, 1990 |
|
Dibenz[a,h]acridine |
226368 |
January 1, 1988 |
|
Dibenz[a,j]acridine |
224420 |
January 1, 1988 |
|
Dibenz[a,h]anthracene |
53703 |
January 1, 1988 |
|
7H-Dibenzo[c,g]carbazole |
194592 |
January 1, 1988 |
|
Dibenzo[a,e]pyrene |
192654 |
January 1, 1988 |
|
Dibenzo[a,h]pyrene |
189640 |
January 1, 1988 |
|
Dibenzo[a,i]pyrene |
189559 |
January 1, 1988 |
|
Dibenzo[a,l]pyrene |
191300 |
January 1, 1988 |
|
1,2-Dibromo-3-chloropropane
(DBCP) |
96128 |
July 1, 1987 |
|
2,3-Dibromo-1-propanol |
96139 |
October 1, 1994 |
|
Dichloroacetic acid |
79436 |
May 1, 1996 |
|
p-Dichlorobenzene |
106467 |
January 1, 1989 |
|
3,3'-Dichlorobenzidine |
91941 |
October 1, 1987 |
|
3,3'-Dichlorobenzidine
dihydrochloride |
612839 |
May 15, 1998 |
|
1,4-Dichloro-2-butene |
764410 |
January 1, 1990 |
|
3,3'-Dichloro-4,4'-diaminodiphenyl
ether |
28434868 |
January 1, 1988 |
|
1,1-Dichloroethane |
75343 |
January 1, 1990 |
|
Dichloromethane (Methylene
chloride) |
75092 |
April 1, 1988 |
|
1,2-Dichloropropane |
78875 |
January 1, 1990 |
|
1,3-Dichloropropene |
542756 |
January 1, 1989 |
|
Dieldrin |
60571 |
July 1, 1988 |
|
Dienestrol |
84173 |
January 1, 1990 |
|
Diepoxybutane |
1464535 |
January 1, 1988 |
|
Diesel engine exhaust |
--- |
October 1, 1990 |
|
Di(2-ethylhexyl)phthalate |
117817 |
January 1, 1988 |
|
1,2-Diethylhydrazine |
1615801 |
January 1, 1988 |
|
Diethyl sulfate |
64675 |
January 1, 1988 |
|
Diethylstilbestrol (DES) |
56531 |
February 27, 1987 |
|
Diglycidyl resorcinol
ether (DGRE) |
101906 |
July 1, 1989 |
|
Dihydrosafrole |
94586 |
January 1, 1988 |
|
Diisopropyl sulfate |
2973106 |
April 1, 1993 |
|
3,3'-Dimethoxybenzidine
(ortho-Dianisidine) |
119904 |
January 1, 1988 |
|
3,3'-Dimethoxybenzidine
dihydrochloride (ortho-Dianisidine dihydrochloride) |
20325400 |
October 1, 1990 |
|
Dimethyl sulfate |
77781 |
January 1, 1988 |
|
4-Dimethylaminoazobenzene |
60117 |
January 1, 1988 |
|
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2- furyl)vinyl]-1,3,4-oxadiazole |
55738540 |
January 1, 1988 |
|
7,12-Dimethylbenz(a)anthracene |
57976 |
January 1, 1990 |
|
3,3'-Dimethylbenzidine
(ortho-Tolidine) |
119937 |
January 1, 1988 |
|
3,3'-Dimethylbenzidine
dihydrochloride |
612828 |
April 1, 1992 |
|
Dimethylcarbamoyl chloride |
79447 |
January 1, 1988 |
|
1,1-Dimethylhydrazine
(UDMH) |
57147 |
October 1, 1989 |
|
1,2-Dimethylhydrazine |
540738 |
January 1, 1988 |
|
Dimethylvinylchloride |
513371 |
July 1, 1989 |
|
3,7-Dinitrofluoranthene |
105735715 |
August 26, 1997 |
|
3,9-Dinitrofluoranthene |
22506532 |
August 26, 1997 |
|
1,6-Dinitropyrene |
42397648 |
October 1, 1990 |
|
1,8-Dinitropyrene |
42397659 |
October 1, 1990 |
|
Dinitrotoluene mixture,
2,4-/2,6- |
--- |
May 1, 1996 |
|
2,4-Dinitrotoluene |
121142 |
July 1, 1988 |
|
2,6-Dinitrotoluene |
606202 |
July 1, 1995 |
|
Di-n-propyl
isocinchomeronate (MGK Repellent 326) |
136458 |
May 1, 1996 |
|
1,4-Dioxane |
123911 |
January 1, 1988 |
|
Diphenylhydantoin
(Phenytoin) |
57410 |
January 1, 1988 |
|
Diphenylhydantoin
(Phenytoin), sodium salt |
630933 |
January 1, 1988 |
|
Direct Black 38 (technical
grade) |
1937377 |
January 1, 1988 |
|
Direct Blue 6 (technical
grade) |
2602462 |
January 1, 1988 |
|
Direct Brown 95 (technical
grade) |
16071866 |
October 1, 1988 |
|
Disperse Blue 1 |
2475458 |
October 1, 1990 |
|
Diuron |
330541 |
May 31, 2002 |
|
|
|
|
|
Epichlorohydrin |
106898 |
October 1, 1987 |
|
Erionite |
12510428/ 66733219 |
October 1, 1988 |
|
Estradiol 17B |
50282 |
January 1, 1988 |
Estragole
|
140670
|
October
29, 1999
|
|
Estrone |
53167 |
January 1, 1988 |
|
Estropipate |
7280377 |
August 26, 1997 |
|
Ethinylestradiol |
57636 |
January 1, 1988 |
|
Ethoprop |
13194484 |
February 27, 2001 |
|
Ethyl acrylate |
140885 |
July 1, 1989 |
|
Ethyl methanesulfonate |
62500 |
January 1, 1988 |
|
Ethyl-4,4'-dichlorobenzilate |
510156 |
January 1, 1990 |
|
Ethylene dibromide |
106934 |
July 1, 1987 |
|
Ethylene dichloride
(1,2-Dichloroethane) |
107062 |
October 1, 1987 |
|
Ethylene oxide |
75218 |
July 1, 1987 |
|
Ethylene thiourea |
96457 |
January 1, 1988 |
|
Ethyleneimine |
151564 |
January 1, 1988 |
|
|
|
|
|
Fenoxycarb |
72490018 |
June 2, 2000 |
|
Folpet |
133073 |
January 1, 1989 |
|
Formaldehyde (gas) |
50000 |
January 1, 1988 |
|
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole |
3570750 |
January 1, 1988 |
Fumonisin
B1
|
116355830 |
November 14,
2003 |
|
Furan |
110009 |
October 1, 1993 |
|
Furazolidone |
67458 |
January 1, 1990 |
|
Furmecyclox |
60568050 |
January 1, 1990 |
|
Fusarin C |
79748815 |
July 1, 1995 |
|
|
|
|
|
Ganciclovir sodium |
82410320 |
August 26, 1997 |
|
Gasoline engine exhaust
(condensates/extracts) |
--- |
October 1, 1990 |
Gemfibrozil
|
25812300
|
December
22, 2000
|
|
Glasswool fibers (airborne
particles of respirable size) |
--- |
July 1, 1990 |
|
Glu-P-1
(2-Amino-6-methyldipyrido[1,2- a:3',2'-d]imidazole) |
67730114 |
January 1, 1990 |
|
Glu-P-2
(2-Aminodipyrido[1,2-a:3',2'-d]imidazole) |
67730103 |
January 1, 1990 |
|
Glycidaldehyde |
765344 |
January 1, 1988 |
|
Glycidol |
556525 |
July 1, 1990 |
|
Griseofulvin |
126078 |
January 1, 1990 |
|
Gyromitrin (Acetaldehyde
methylformylhydrazone) |
16568028 |
January 1, 1988 |
|
|
|
|
|
HC Blue 1 |
2784943 |
July 1, 1989 |
|
Heptachlor |
76448 |
July 1, 1988 |
|
Heptachlor epoxide |
1024573 |
July 1, 1988 |
|
Hexachlorobenzene |
118741 |
October 1, 1987 |
|
Hexachlorocyclohexane
(technical grade) |
--- |
October 1, 1987 |
|
Hexachlorodibenzodioxin |
34465468 |
April 1, 1988 |
|
Hexachloroethane |
67721 |
July 1, 1990 |
|
Hexamethylphosphoramide |
680319 |
January 1, 1988 |
|
Hydrazine |
302012 |
January 1, 1988 |
|
Hydrazine sulfate |
10034932 |
January 1, 1988 |
|
Hydrazobenzene
(1,2-Diphenylhydrazine) |
122667 |
January 1, 1988 |
|
|
|
|
|
Indeno [1,2,3-cd]pyrene |
193395 |
January 1, 1988 |
Indium
phosphide
|
22398807
|
February
27, 2001
|
|
IQ
(2-Amino-3-methylimidazo[4,5-f]quinoline) |
76180966 |
April 1, 1990 |
|
Iprodione |
36734197 |
May 1, 1996 |
|
Iron dextran complex |
9004664 |
January 1, 1988 |
|
Isobutyl nitrite |
542563 |
May 1, 1996 |
|
Isoprene |
78795 |
May 1, 1996 |
|
Isosafrole |
120581 |
October 1, 1989 |
Isoxaflutole
|
141112290
|
December
22, 2000
|
|
|
|
|
|
Lactofen |
77501634 |
January 1, 1989 |
|
Lasiocarpine |
303344 |
April 1, 1988 |
|
Lead acetate |
301042 |
January 1, 1988 |
|
Lead and lead compounds |
--- |
October 1, 1992 |
|
Lead phosphate |
7446277 |
April 1, 1988 |
|
Lead subacetate |
1335326 |
October 1, 1989 |
|
Lindane and other
hexachlorocyclohexane isomers |
--- |
October 1, 1989 |
Lynestrenol
|
52766
|
February
27, 2001
|
|
|
|
|
|
Mancozeb |
8018017 |
January 1, 1990 |
|
Maneb |
12427382 |
January 1, 1990 |
|
Me-A-alpha-C
(2-Amino-3-methyl-9H-pyrido[2,3-b]indole) |
68006837 |
January 1, 1990 |
|
Medroxyprogesterone
acetate |
71589 |
January 1, 1990 |
|
MeIQ(2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) |
77094112 |
October 1, 1994 |
|
MeIQx(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) |
77500040 |
October 1, 1994 |
|
Melphalan |
148823 |
February 27, 1987 |
|
Merphalan |
531760 |
April 1, 1988 |
|
Mestranol |
72333 |
April 1, 1988 |
|
Metham sodium |
137428 |
November 6, 1998 |
|
8-Methoxypsoralen with
ultraviolet A therapy |
298817 |
February 27, 1987 |
|
5-Methoxypsoralen with
ultraviolet A therapy |
484208 |
October 1, 1988 |
|
2-Methylaziridine
(Propyleneimine) |
75558 |
January 1, 1988 |
|
Methylazoxymethanol |
590965 |
April 1, 1988 |
|
Methylazoxymethanol
acetate |
592621 |
April 1, 1988 |
|
Methyl carbamate |
598550 |
May 15, 1998 |
|
3-Methylcholanthrene |
56495 |
January 1, 1990 |
|
5-Methylchrysene |
3697243 |
April 1, 1988 |
|
4,4'-Methylene
bis(2-chloroaniline) |
101144 |
July 1, 1987 |
|
4,4'-Methylene
bis(N,N-dimethyl)benzenamine |
101611 |
October 1, 1989 |
|
4,4'-Methylene
bis(2-methylaniline) |
838880 |
April 1, 1988 |
|
4,4'-Methylenedianiline |
101779 |
January 1, 1988 |
|
4,4'-Methylenedianiline
dihydrochloride |
13552448 |
January 1, 1988 |
|
Methyleugenol |
93152 |
November 16, 2001 |
|
Methylhydrazine and its
salts |
--- |
July 1, 1992 |
|
Methyl iodide |
74884 |
April 1, 1988 |
|
Methylmercury compounds |
--- |
May 1, 1996 |
|
Methyl methanesulfonate |
66273 |
April 1, 1988 |
|
2-Methyl-1-nitroanthraquinone
(of uncertain purity) |
129157 |
April 1, 1988 |
|
N-Methyl-N'-nitro-N-nitrosoguanidine |
70257 |
April 1, 1988 |
|
N-Methylolacrylamide |
924425 |
July 1, 1990 |
|
Methylthiouracil |
56042 |
October 1, 1989 |
|
Metiram |
9006422 |
January 1, 1990 |
|
Metronidazole |
443481 |
January 1, 1988 |
|
Michler's ketone |
90948 |
January 1, 1988 |
|
Mirex |
2385855 |
January 1, 1988 |
|
Mitomycin C |
50077 |
April 1, 1988 |
|
Monocrotaline |
315220 |
April 1, 1988 |
|
5-(Morpholinomethyl)-3-[(5-nitro-furfurylidene)-
amino] -2-oxazolidinone |
139913 |
April 1, 1988 |
|
Mustard Gas |
505602 |
February 27, 1987 |
MX
(3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone)
|
77439760
|
December
22, 2000
|
|
|
|
|
|
Nafenopin |
3771195 |
April 1, 1988 |
|
Nalidixic acid |
389082 |
May 15, 1998 |
|
Naphthalene |
91203 |
April 19, 2002 |
|
1-Naphthylamine |
134327 |
October 1, 1989 |
|
2-Naphthylamine |
91598 |
February 27, 1987 |
|
Nickel (Metallic) |
7440020 |
October 1, 1989 |
Nickel acetate
|
373024 |
October 1, 1989 |
|
Nickel carbonate |
3333673 |
October 1, 1989 |
|
Nickel carbonyl |
13463393 |
October 1, 1987 |
Nickel hydroxide
|
12054487; |
October 1, 1989 |
|
|
12125563 |
|
Nickelocene
|
1271289 |
October 1, 1989 |
|
Nickel oxide |
1313991 |
October 1, 1989 |
|
Nickel refinery dust from
the pyrometallurgical process |
--- |
October 1, 1987 |
|
Nickel subsulfide |
12035722 |
October 1, 1987 |
|
Niridazole |
61574 |
April 1, 1988 |
|
Nitrilotriacetic acid |
139139 |
January 1, 1988 |
|
Nitrilotriacetic acid,
trisodium salt monohydrate |
18662538 |
April 1, 1989 |
|
5-Nitroacenaphthene |
602879 |
April 1, 1988 |
|
5-Nitro-o-anisidine |
99592 |
October 1, 1989 |
|
o-Nitroanisole |
91236 |
October 1, 1992 |
|
Nitrobenzene |
98953 |
August 26, 1997 |
|
4-Nitrobiphenyl |
92933 |
April 1, 1988 |
|
6-Nitrochrysene |
7496028 |
October 1, 1990 |
|
Nitrofen (technical grade) |
1836755 |
January 1, 1988 |
|
2-Nitrofluorene |
607578 |
October 1, 1990 |
|
Nitrofurazone |
59870 |
January 1, 1990 |
|
1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone |
555840 |
April 1, 1988 |
|
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide |
531828 |
April 1, 1988 |
|
Nitrogen mustard
(Mechlorethamine) |
51752 |
January 1, 1988 |
|
Nitrogen mustard
hydrochloride (Mechlorethamine hydrochloride) |
55867 |
April 1, 1988 |
|
Nitrogen mustard N-oxide |
126852 |
April 1, 1988 |
|
Nitrogen mustard N-oxide
hydrochloride |
302705 |
April 1, 1988 |
|
Nitromethane |
75525 |
May 1, 1997 |
|
2-Nitropropane |
79469 |
January 1, 1988 |
|
1-Nitropyrene |
5522430 |
October 1, 1990 |
|
4-Nitropyrene |
57835924 |
October 1, 1990 |
|
N-Nitrosodi-n-butylamine |
924163 |
October 1, 1987 |
|
N-Nitrosodiethanolamine |
1116547 |
January 1, 1988 |
|
N-Nitrosodiethylamine |
55185 |
October 1, 1987 |
|
N-Nitrosodimethylamine |
62759 |
October 1, 1987 |
|
p-Nitrosodiphenylamine |
156105 |
January 1, 1988 |
|
N-Nitrosodiphenylamine |
86306 |
April 1, 1988 |
|
N-Nitrosodi-n-propylamine |
621647 |
January 1, 1988 |
|
N-Nitroso-N-ethylurea |
759739 |
October 1, 1987 |
|
3-(N-Nitrosomethylamino)propionitrile |
60153493 |
April 1, 1990 |
|
4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone |
64091914 |
April 1, 1990 |
|
N-Nitrosomethylethylamine |
10595956 |
October 1, 1989 |
|
N-Nitroso-N-methylurea |
684935 |
October 1, 1987 |
|
N-Nitroso-N-methylurethane |
615532 |
April 1, 1988 |
|
N-Nitrosomethylvinylamine |
4549400 |
January 1, 1988 |
|
N-Nitrosomorpholine |
59892 |
January 1, 1988 |
|
N-Nitrosonornicotine |
16543558 |
January 1, 1988 |
|
N-Nitrosopiperidine |
100754 |
January 1, 1988 |
|
N-Nitrosopyrrolidine |
930552 |
October 1, 1987 |
|
N-Nitrososarcosine |
13256229 |
January 1, 1988 |
|
o-Nitrotoluene |
88722 |
May 15, 1998 |
|
Norethisterone
(Norethindrone) |
68224 |
October 1, 1989 |
|
Norethynodrel |
68235 |
February 27, 2001 |
|
|
|
|
|
Ochratoxin A |
303479 |
July 1, 1990 |
|
Oil Orange SS |
2646175 |
April 1, 1988 |
|
Oral contraceptives,
combined |
--- |
October 1, 1989 |
|
Oral contraceptives,
sequential |
--- |
October 1, 1989 |
|
Oxadiazon |
19666309 |
July 1, 1991 |
|
Oxazepam |
604751 |
October 1, 1994 |
|
Oxymetholone |
434071 |
January 1, 1988 |
Oxythioquinox
|
2439012
|
August 20, 1999
|
|
|
|
|
|
Palygorskite
fibers (> 5mm in length) |
12174117 |
December
28, 1999 |
|
Panfuran S |
794934 |
January 1, 1988 |
|
Pentachlorophenol |
87865 |
January 1, 1990 |
|
Phenacetin |
62442 |
October 1, 1989 |
|
Phenazopyridine |
94780 |
January 1, 1988 |
|
Phenazopyridine
hydrochloride |
136403 |
January 1, 1988 |
|
Phenesterin |
3546109 |
July 1, 1989 |
|
Phenobarbital |
50066 |
January 1, 1990 |
|
Phenolphthalein |
77098 |
May 15, 1998 |
|
Phenoxybenzamine |
59961 |
April 1, 1988 |
|
Phenoxybenzamine
hydrochloride |
63923 |
April 1, 1988 |
|
o-Phenylenediamine and its
salts |
95545 |
May 15, 1998 |
|
Phenyl glycidyl ether |
122601 |
October 1, 1990 |
|
Phenylhydrazine and its
salts |
--- |
July 1, 1992 |
|
o-Phenylphenate, sodium |
132274 |
January 1, 1990 |
|
o-Phenylphenol |
90437 |
August 4, 2000 |
|
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine) |
105650235 |
October 1, 1994 |
|
Polybrominated biphenyls |
--- |
January 1, 1988 |
|
Polychlorinated biphenyls |
--- |
October 1, 1989 |
|
Polychlorinated biphenyls
(containing 60 or more percent chlorine by molecular weight) |
--- |
January 1, 1988 |
|
Polychlorinated
dibenzo-p-dioxins |
--- |
October 1, 1992 |
|
Polychlorinated
dibenzofurans |
--- |
October 1, 1992 |
|
Polygeenan |
53973981 |
January 1, 1988 |
|
Ponceau MX |
3761533 |
April 1, 1988 |
|
Ponceau 3R |
3564098 |
April 1, 1988 |
|
Potassium bromate |
7758012 |
January 1, 1990 |
|
Primidone |
125337 |
August 20, 1999 |
|
Procarbazine |
671169 |
January 1, 1988 |
|
Procarbazine hydrochloride |
366701 |
January 1, 1988 |
|
Procymidone |
32809168 |
October 1, 1994 |
|
Progesterone |
57830 |
January 1, 1988 |
|
Pronamide |
23950585 |
May 1, 1996 |
Propachlor
|
1918167
|
February
27, 2001
|
|
1,3-Propane sultone |
1120714 |
January 1, 1988 |
|
Propargite |
2312358 |
October 1, 1994 |
|
beta-Propiolactone |
57578 |
January 1, 1988 |
|
Propylene oxide |
75569 |
October 1, 1988 |
|
Propylthiouracil |
51525 |
January 1, 1988 |
|
Pyridine |
110861 |
May 17, 2002 |
|
|
|
|
|
Quinoline and its strong
acid salts |
--- |
October 24, 1997 |
|
|
|
|
|
Radionuclides |
--- |
July 1, 1989 |
|
Reserpine |
50555 |
October 1, 1989 |
|
Residual (heavy) fuel oils |
--- |
October 1, 1990 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Safrole |
94597 |
January 1, 1988 |
|
Salicylazosulfapyridine |
599791 |
May 15, 1998 |
|
Selenium sulfide |
7446346 |
October 1, 1989 |
|
Shale-oils |
68308349 |
April 1, 1990 |
|
Silica, crystalline
(airborne particles of respirable size) |
--- |
October 1, 1988 |
|
Soots, tars, and mineral
oils (untreated and mildly treated oils and used engine oils) |
--- |
February 27, 1987 |
|
Spironolactone |
52017 |
May 1, 1997 |
|
Stanozolol |
10418038 |
May 1, 1997 |
|
Sterigmatocystin |
10048132 |
April 1, 1988 |
|
Streptozotocin
(streptozocin) |
18883664 |
January 1, 1988 |
Strong inorganic
acid mists containing sulfuric acid
|
--- |
March 14, 2003 |
|
Styrene oxide |
96093 |
October 1, 1988 |
|
Sulfallate |
95067 |
January 1, 1988 |
|
|
|
|
|
Talc containing
asbestiform fibers |
--- |
April 1, 1990 |
|
Tamoxifen and its salts |
10540291 |
September 1, 1996 |
|
Terrazole |
2593159 |
October 1, 1994 |
|
Testosterone and its
esters |
58220 |
April 1, 1988 |
|
2,3,7,8-Tetrachlorodibenzo-para-dioxin
(TCDD) |
1746016 |
January 1, 1988 |
|
1,1,2,2-Tetrachloroethane |
79345 |
July 1, 1990 |
|
Tetrachloroethylene
(Perchloroethylene) |
127184 |
April 1, 1988 |
|
p-a,a,a-Tetrachlorotoluene |
5216251 |
January 1, 1990 |
|
Tetrafluoroethylene |
116143 |
May 1, 1997 |
|
Tetranitromethane |
509148 |
July 1, 1990 |
|
Thioacetamide |
62555 |
January 1, 1988 |
|
4,4'-Thiodianiline |
139651 |
April 1, 1988 |
|
Thiodicarb |
59669260 |
August 20, 1999 |
|
Thiourea |
62566 |
January 1, 1988 |
|
Thorium dioxide |
1314201 |
February 27, 1987 |
|
Tobacco, oral use of
smokeless products |
--- |
April 1, 1988 |
|
Tobacco smoke |
--- |
April 1, 1988 |
|
Toluene diisocyanate |
26471625 |
October 1, 1989 |
|
ortho-Toluidine |
95534 |
January 1, 1988 |
|
ortho-Toluidine
hydrochloride |
636215 |
January 1, 1988 |
|
|
|
|
|
Toxaphene (Polychlorinated
camphenes) |
8001352 |
January 1, 1988 |
|
Treosulfan |
299752 |
February 27, 1987 |
|
Trichlormethine
(Trimustine hydrochloride) |
817094 |
January 1, 1992 |
|
Trichloroethylene |
79016 |
April 1, 1988 |
|
2,4,6-Trichlorophenol |
88062 |
January 1, 1988 |
|
1,2,3-Trichloropropane |
96184 |
October 1,1992 |
|
Trimethyl phosphate |
512561 |
May 1, 1996 |
|
2,4,5-Trimethylaniline and
its strong acid salts |
--- |
October 24, 1997 |
|
Triphenyltin hydroxide |
76879 |
July 1, 1992 |
|
|
|
|
|
Tris(aziridinyl)-para-benzoquinone
(Triaziquone) |
68768 |
October 1, 1989 |
|
Tris(1-aziridinyl)phosphine
sulfide (Thiotepa) |
52244 |
January 1, 1988 |
|
Tris(2-chloroethyl)
phosphate |
115968 |
April 1, 1992 |
|
Tris(2,3-dibromopropyl)phosphate |
126727 |
January 1, 1988 |
|
Trp-P-1 (Tryptophan-P-1) |
62450060 |
April 1, 1988 |
|
Trp-P-2 (Tryptophan-P-2) |
62450071 |
April 1, 1988 |
|
Trypan blue (commercial
grade) |
72571 |
October 1, 1989 |
|
|
|
|
|
Unleaded gasoline (wholly
vaporized) |
--- |
April 1, 1988 |
|
Uracil mustard |
66751 |
April 1, 1988 |
|
Urethane (Ethyl carbamate) |
51796 |
January 1, 1988 |
|
|
|
|
|
Vinclozolin |
50471448 |
August 20, 1999 |
|
Vinyl bromide |
593602 |
October 1, 1988 |
|
Vinyl chloride |
75014 |
February 27, 1987 |
|
4-Vinylcyclohexene |
100403 |
May 1, 1996 |
|
4-Vinyl-1-cyclohexene
diepoxide (Vinyl cyclohexenedioxide) |
106876 |
July 1, 1990 |
|
Vinyl fluoride |
75025 |
May 1, 1997 |
|
Vinyl trichloride
(1,1,2-Trichloroethane) |
79005 |
October 1, 1990 |
|
|
|
|
|
2,6-Xylidine
(2,6-Dimethylaniline) |
87627 |
January 1, 1991 |
|
|
|
|
Zileuton
|
111406872
|
December
22, 2000
|
|
|
|
|
CHEMICALS KNOWN TO THE STATE TO CAUSE REPRODUCTIVE
TOXICITY
|
Chemical |
Type of Reproductive
Toxicity |
CAS No. |
Date Listed |
|
|
|
|
|
|
Acetazolamide |
developmental |
59665 |
August 20, 1999 |
|
Acetohydroxamic acid |
developmental |
546883 |
April 1, 1990 |
|
Actinomycin D |
developmental |
50760 |
October 1, 1992 |
|
All-trans retinoic acid |
developmental |
302794 |
January 1, 1989 |
|
Alprazolam |
developmental |
28981977 |
July 1, 1990 |
|
Altretamine |
developmental, male |
645056 |
August 20, 1999 |
Amantadine
hydrochloride
|
developmental
|
665667
|
February
27, 2001
|
|
Amikacin sulfate |
developmental |
39831555 |
July 1, 1990 |
|
Aminoglutethimide |
developmental |
125848 |
July 1, 1990 |
|
Aminoglycosides |
developmental |
--- |
October 1, 1992 |
|
Aminopterin |
developmental, female |
54626 |
July 1, 1987 |
|
Amiodarone hydrochloride |
developmental, female,
male |
19774824 |
August 26, 1997 |
|
Amitraz |
developmental |
33089611 |
March 30, 1999 |
|
Amoxapine |
developmental |
14028445 |
May 15, 1998 |
|
Anabolic steroids |
female, male |
--- |
April 1, 1990 |
|
Angiotensin converting
enzyme (ACE) inhibitors |
developmental |
--- |
October 1, 1992 |
|
|
|
|
|
|
Anisindione |
developmental |
117373 |
October 1, 1992 |
|
Arsenic (inorganic oxides)
|
developmental |
--- |
May 1, 1997 |
|
Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or complications during delivery) |
developmental, female |
50782 |
July 1, 1990 |
|
Atenolol |
developmental |
29122687 |
August 26, 1997 |
|
Auranofin |
developmental |
34031328 |
January 29, 1999 |
|
Azathioprine |
developmental |
446866 |
September 1, 1996 |
|
|
|
|
|
|
Barbiturates |
developmental |
--- |
October 1, 1992 |
|
Beclomethasone
dipropionate |
developmental |
5534098 |
May 15, 1998 |
|
Benomyl |
developmental, male |
17804352 |
July 1, 1991 |
|
Benzene |
developmental, male |
71432 |
December 26, 1997 |
|
Benzodiazepines |
developmental |
--- |
October 1, 1992 |
|
Benzphetamine
hydrochloride |
developmental |
5411223 |
April 1, 1990 |
|
Bischloroethyl nitrosourea
(BCNU) (Carmustine) |
developmental |
154938 |
July 1, 1990 |
|
Bromacil lithium salt |
developmental |
53404196 |
May 18, 1999 |
|
|
male |
|
January 17, 2003 |
|
Bromoxynil |
developmental |
1689845 |
October 1, 1990 |
|
Bromoxynil octanoate |
developmental |
1689992 |
May 18, 1999 |
|
Butabarbital sodium |
developmental |
143817 |
October 1, 1992 |
|
1,4-Butanediol
dimethane-sulfonate (Busulfan) |
developmental |
55981 |
January 1, 1989 |
|
|
|
|
|
|
Cadmium |
developmental, male |
--- |
May 1, 1997 |
|
Carbamazepine |
developmental |
298464 |
January 29, 1999 |
|
Carbon disulfide |
developmental, female,
male |
75150 |
July 1, 1989 |
|
Carbon monoxide |
developmental |
630080 |
July 1, 1989 |
|
Carboplatin |
developmental |
41575944 |
July 1, 1990 |
|
Chenodiol |
developmental |
474259 |
April 1, 1990 |
|
Chinomethionat
(Oxythioquinox)
|
developmental |
2439012 |
November
6, 1998 |
|
Chlorambucil |
developmental |
305033 |
January 1, 1989 |
|
Chlorcyclizine hydrochloride
|
developmental |
1620219 |
July 1, 1987 |
|
Chlordecone (Kepone) |
developmental |
143500 |
January 1, 1989 |
|
Chlordiazepoxide |
developmental |
58253 |
January 1, 1992 |
|
Chlordiazepoxide
hydrochloride |
developmental |
438415 |
January 1, 1992 |
|
1-(2-Chloroethyl)-3-cyclohexyl-1-
nitrosourea (CCNU) (Lomustine) |
developmental |
13010474 |
July 1, 1990 |
|
Chlorsulfuron |
developmental, female,
male |
64902723 |
May 14, 1999 |
|
Cidofovir |
developmental, female,
male |
113852372 |
January 29, 1999 |
|
Cladribine |
developmental |
4291638 |
September 1, 1996 |
|
Clarithromycin |
developmental |
81103119 |
May 1, 1997 |
|
Clobetasol propionate |
developmental, female |
25122467 |
May 15, 1998 |
|
Clomiphene citrate |
developmental |
50419 |
April 1, 1990 |
|
Clorazepate dipotassium |
developmental |
57109907 |
October 1, 1992 |
|
Cocaine |
developmental, female |
50362 |
July 1, 1989 |
|
Codeine phosphate |
developmental |
52288 |
May 15, 1998 |
|
Colchicine |
developmental, male |
64868 |
October 1, 1992 |
|
Conjugated estrogens |
developmental |
--- |
April 1, 1990 |
|
Cyanazine |
developmental |
21725462 |
April 1, 1990 |
|
Cycloate |
developmental |
1134232 |
March 19, 1999 |
|
|
|
|
|
|
Cycloheximide |
developmental |
66819 |
January 1, 1989 |
|
Cyclophosphamide
(anhydrous) |
developmental, female,
male |
50180 |
January 1, 1989 |
|
Cyclophosphamide
(hydrated) |
developmental, female,
male |
6055192 |
January 1, 1989 |
|
Cyhexatin |
developmental |
13121705 |
January 1, 1989 |
|
Cytarabine |
developmental |
147944 |
January 1, 1989 |
|
|
|
|
|
|
Dacarbazine |
developmental |
4342034 |
January 29, 1999 |
|
Danazol |
developmental |
17230885 |
April 1, 1990 |
|
Daunorubicin hydrochloride
|
developmental |
23541506 |
July 1, 1990 |
|
2,4-D butyric acid |
|
94826 |
June 18, 1999 |
|
o,p'-DDT |
developmental, female,
male |
789026 |
May 15, 1998 |
|
p,p'-DDT |
developmental, female,
male |
50293 |
May 15, 1998 |
|
|
|
|
|
|
Demeclocycline
hydrochloride (internal use) |
developmental |
64733 |
January 1, 1992 |
|
Diazepam |
developmental |
439145 |
January 1, 1992 |
Diazoxide
|
developmental
|
364987
|
February
27, 2001
|
|
1,2-Dibromo-3-chloropropane (DBCP) |
male |
96128 |
February 27, 1987 |
|
Dichlorophene |
developmental |
97234 |
April 27, 1999 |
Dichlorphenamide
|
developmental
|
120978
|
February
27, 2001
|
|
Diclofop methyl |
developmental |
51338273 |
March 5, 1999 |
|
Dicumarol |
developmental |
66762 |
October 1, 1992 |
Di(2-ethylhexyl)phthalate
(DEHP)
|
developmental, male |
117817 |
October 24, 2003 |
|
Diethylstilbestrol (DES) |
developmental |
56531 |
July 1, 1987 |
|
Diflunisal |
developmental, female |
22494424 |
January 29, 1999 |
|
Dihydroergotamine mesylate
|
developmental |
6190392 |
May 1, 1997 |
Diltiazem
hydrochloride
|
developmental
|
33286225
|
February
27, 2001
|
|
m-Dinitrobenzene |
male |
99650 |
July 1, 1990 |
|
o-Dinitrobenzene |
male |
528290 |
July 1, 1990 |
|
p-Dinitrobenzene |
male |
100254 |
July 1, 1990 |
|
2,4-Dinitrotoluene |
male |
121142 |
August 20, 1999 |
|
2,6-Dinitrotoluene |
male |
606202 |
August 20, 1999 |
|
Dinitrotoluene (technical
grade) |
female, male |
--- |
August 20, 1999 |
|
Dinocap |
developmental |
39300453 |
April 1, 1990 |
|
Dinoseb |
developmental, male |
88857 |
January 1, 1989 |
|
Diphenylhydantoin
(Phenytoin) |
developmental |
57410 |
July 1, 1987 |
|
Disodium cyanodithio-imidocarbonate |
developmental |
138932 |
March 30, 1999 |
|
Doxorubicin hydrochloride |
developmental, male |
23214928 |
January 29, 1999 |
|
Doxycycline (internal use)
|
developmental |
564250 |
July 1, 1990 |
|
Doxycycline calcium
(internal use) |
developmental |
94088854 |
January 1, 1992 |
|
Doxycycline hyclate
(internal use) |
developmental |
24390145 |
October 1, 1991 |
|
Doxycycline
monohydrate (internal use) |
developmental |
17086281 |
October 1, 1991 |
|
|
|
|
|
|
Endrin |
developmental |
72208 |
May 15, 1998 |
|
Epichlorohydrin |
male |
106898 |
September 1, 1996 |
|
Ergotamine tartrate |
developmental |
379793 |
April 1, 1990 |
|
Estropipate |
developmental |
7280377 |
August 26, 1997 |
|
Ethionamide |
developmental |
536334 |
August 26, 1997 |
|
Ethyl alcohol in
alcoholic beverages |
developmental |
--- |
October 1, 1987 |
|
Ethyl
dipropylthiocarbamate |
developmental |
759944 |
April 27, 1999 |
|
Ethylene dibromide |
developmental, male |
106934 |
May 15, 1998 |
|
Ethylene glycol monoethyl
ether |
developmental, male |
110805 |
January 1, 1989 |
|
Ethylene glycol monomethyl
ether |
developmental, male |
109864 |
January 1, 1989 |
|
Ethylene glycol monoethyl
ether acetate |
developmental, male |
111159 |
January 1, 1993 |
|
Ethylene glycol monomethyl
ether acetate |
developmental, male |
110496 |
January 1, 1993 |
|
Ethylene oxide |
female |
75218 |
February 27, 1987 |
|
Ethylene thiourea |
developmental |
96457 |
January 1, 1993 |
Etodolac
|
developmental,
female
|
41340254
|
August
20, 1999
|
|
Etoposide |
developmental |
33419420 |
July 1, 1990 |
|
Etretinate |
developmental |
54350480 |
July 1, 1987 |
|
|
|
|
|
|
Fenoxaprop ethyl |
developmental |
66441234 |
March 26, 1999 |
Filgrastim
|
developmental
|
121181531
|
February
27, 2001
|
|
Fluazifop butyl |
developmental |
69806504 |
November 6, 1998 |
|
Flunisolide |
developmental, female |
3385033 |
May 15, 1998 |
|
Fluorouracil |
developmental |
51218 |
January 1, 1989 |
|
Fluoxymesterone |
developmental |
76437 |
April 1, 1990 |
|
Flurazepam hydrochloride |
developmental |
1172185 |
October 1, 1992 |
Flurbiprofen
|
developmental,
female
|
5104494
|
August
20, 1999
|
|
Flutamide |
developmental |
13311847 |
July 1, 1990 |
|
Fluticasone propionate |
developmental |
80474142 |
May 15, 1998 |
|
Fluvalinate |
developmental |
69409945 |
November 6, 1998 |
|
|
|
|
|
|
Ganciclovir sodium |
developmental, male |
82410320 |
August 26, 1997 |
|
Gemfibrozil |
female, male |
25812300 |
August 20, 1999 |
|
Goserelin acetate |
developmental, female,
male |
65807025 |
August 26, 1997 |
|
|
|
|
|
|
Halazepam |
developmental |
23092173 |
July 1, 1990 |
|
Halobetasol propionate |
developmental |
66852548 |
August 20, 1999 |
|
Haloperidol |
developmental, female |
52868 |
January 29, 1999 |
|
Halothane |
developmental |
151677 |
September 1, 1996 |
|
Heptachlor |
developmental |
76448 |
August 20, 1999 |
|
Hexachlorobenzene |
developmental |
118741 |
January 1, 1989 |
|
Hexamethylphosphoramide |
male |
680319 |
October 1, 1994 |
|
Histrelin acetate |
developmental |
--- |
May 15, 1998 |
|
Hydramethylnon |
developmental, male |
67485294 |
March 5, 1999 |
|
Hydroxyurea |
developmental |
127071 |
May 1, 1997 |
|
|
|
|
|
|
Idarubicin hydrochloride |
developmental, male |
57852570 |
August 20, 1999 |
|
Ifosfamide |
developmental |
3778732 |
July 1, 1990 |
|
Iodine-131 |
developmental |
10043660 |
January 1, 1989 |
|
Isotretinoin |
developmental |
4759482 |
July 1, 1987 |
|
|
|
|
|
|
Lead |
developmental, female,
male |
--- |
February 27, 1987 |
|
Leuprolide acetate |
developmental, female,
male |
74381536 |
August 26, 1997 |
|
Levodopa |
developmental |
59927 |
January 29, 1999 |
|
Levonorgestrel implants |
female |
797637 |
May 15, 1998 |
|
Linuron |
developmental |
330552 |
March 19, 1999 |
|
Lithium carbonate |
developmental |
554132 |
January 1, 1991 |
|
Lithium citrate |
developmental |
919164 |
January 1, 1991 |
|
Lorazepam |
developmental |
846491 |
July 1, 1990 |
|
Lovastatin |
developmental |
75330755 |
October 1, 1992 |
|
|
|
|
|
|
Mebendazole |
developmental |
31431397 |
August 20, 1999 |
|
Medroxyprogesterone
acetate |
developmental |
71589 |
April 1, 1990 |
|
Megestrol acetate |
developmental |
595335 |
January 1, 1991 |
|
Melphalan |
developmental |
148823 |
July 1, 1990 |
|
Menotropins |
developmental |
9002680 |
April 1, 1990 |
|
Meprobamate |
developmental |
57534 |
January 1, 1992 |
|
Mercaptopurine |
developmental |
6112761 |
July 1, 1990 |
|
Mercury and mercury
compounds |
developmental |
--- |
July 1, 1990 |
|
Methacycline hydrochloride
|
developmental |
3963959 |
January 1, 1991 |
|
Metham sodium |
developmental |
137428 |
May 15, 1998 |
|
Methazole |
developmental |
20354261 |
December 1, 1999 |
|
Methimazole |
developmental |
60560 |
July 1, 1990 |
|
Methotrexate |
developmental |
59052 |
January 1, 1989 |
|
Methotrexate sodium |
developmental |
15475566 |
April 1, 1990 |
|
Methyl bromide as a
structural fumigant |
developmental |
74839 |
January 1, 1993 |
|
Methyl chloride |
developmental |
74873 |
March 10, 2000 |
|
Methyl mercury |
developmental |
--- |
July 1, 1987 |
N-Methylpyrrolidone
|
developmental
|
872504
|
June
15, 2001
|
|
Methyltestosterone |
developmental |
58184 |
April 1, 1990 |
|
Metiram |
developmental |
9006422 |
March 30, 1999 |
|
Midazolam hydrochloride |
developmental |
59467968 |
July 1, 1990 |
|
Minocycline hydrochloride
(internal use) |
developmental |
13614987 |
January 1, 1992 |
|
Misoprostol |
developmental |
59122462 |
April 1, 1990 |
|
Mitoxantrone hydrochloride
|
developmental |
70476823 |
July 1, 1990 |
|
Myclobutanil |
developmental, male |
88671890 |
April 16, 1999 |
|
|
|
|
|
|
Nabam |
developmental |
142596 |
March 30, 1999 |
|
Nafarelin acetate |
developmental |
86220420 |
April 1, 1990 |
|
Neomycin sulfate (internal
use) |
developmental |
1405103 |
October 1, 1992 |
|
Netilmicin sulfate |
developmental |
56391572 |
July 1, 1990 |
|
Nickel carbonyl |
developmental |
13463393 |
September 1, 1996 |
|
Nicotine |
developmental |
54115 |
April 1, 1990 |
|
Nifedipine |
developmental, female,
male |
21829254 |
January 29, 1999 |
Nimodipine
|
developmental
|
66085594
|
April
24, 2001
|
|
Nitrapyrin |
developmental |
1929824 |
March 30, 1999 |
|
Nitrofurantoin |
male |
67209 |
April 1, 1991 |
|
Nitrogen mustard
(Mechlorethamine) |
developmental |
51752 |
January 1, 1989 |
|
Nitrogen mustard
hydrochloride (Mechlorethamine hydrochloride) |
developmental |
55867 |
July 1, 1990 |
|
Norethisterone
(Norethindrone) |
developmental |
68224 |
April 1, 1990 |
|
Norethisterone acetate
(Norethindrone acetate) |
developmental |
51989 |
October 1, 1991 |
|
Norethisterone
(Norethindrone)/ Ethinyl estradiol |
developmental |
68224/57636 |
April 1, 1990 |
|
Norethisterone
(Norethindrone) /Mestranol |
developmental |
68224/72333 |
April 1, 1990 |
|
Norgestrel |
developmental |
6533002 |
April 1, 1990 |
|
|
|
|
|
|
Oxadiazon |
developmental |
19666309 |
May 15, 1998 |
|
Oxazepam |
developmental |
604751 |
October 1, 1992 |
|
Oxydemeton methyl |
female, male |
301122 |
November 6, 1998 |
|
Oxymetholone |
developmental |
434071 |
May 1, 1997 |
|
Oxytetracycline (internal
use) |
developmental |
79572 |
January 1, 1991 |
|
Oxytetracycline
hydrochloride (internal use) |
developmental |
2058460 |
October 1, 1991 |
|
|
|
|
|
|
Paclitaxel |
developmental, female,
male |
33069624 |
August 26, 1997 |
|
Paramethadione |
developmental |
115673 |
July 1, 1990 |
|
Penicillamine |
developmental |
52675 |
January 1, 1991 |
|
Pentobarbital sodium |
developmental |
57330 |
July 1, 1990 |
|
Pentostatin |
developmental |
53910251 |
September 1, 1996 |
|
Phenacemide |
developmental |
63989 |
July 1, 1990 |
|
Phenprocoumon |
developmental |
435972 |
October 1, 1992 |
Pimozide
|
developmental,
female
|
2062784
|
August
20, 1999
|
|
Pipobroman |
developmental |
54911 |
July 1, 1990 |
|
Plicamycin |
developmental |
18378897 |
April 1, 1990 |
|
Polybrominated biphenyls |
developmental |
--- |
October 1, 1994 |
|
Polychlorinated biphenyls |
developmental |
--- |
January 1, 1991 |
|
Potassium
dimethyldithio-carbamate |
developmental |
128030 |
March 30 1999 |
|
Pravastatin sodium |
developmental |
81131706 |
March 3, 2000 |
|
Prednisolone sodium
phosphate |
developmental |
125020 |
August 20, 1999 |
|
Procarbazine hydrochloride
|
developmental |
366701 |
July 1, 1990 |
|
Propargite |
developmental |
2312358 |
June 15, 1999 |
|
Propylthiouracil |
developmental |
51525 |
July 1, 1990 |
|
Pyrimethamine |
developmental |
58140 |
January 29, 1999 |
|
|
|
|
|
|
Quazepam |
developmental |
36735225 |
August 26, 1997 |
|
Quizalofop-ethyl |
male |
76578148 |
December
24, 1999 |
|
|
|
|
|
|
Resmethrin |
developmental |
10453868 |
November 6, 1998 |
|
Retinol/retinyl esters,
when in daily dosages in excess of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/reinyl esters are required and essential for maintenance of normal reproductive function.
The recommended daily level during pregnancy is 8,000 IU.) |
developmental |
--- |
July 1, 1989 |
|
Ribavirin |
Developmental |
36791045 |
April 1, 1990 |
|
Ribavirin |
male |
36791045 |
February 27, 2001 |
|
Rifampin |
developmental, female |
13292461 |
February 27, 2001 |
|
|
|
|
|
|
Secobarbital sodium |
developmental |
309433 |
October 1, 1992 |
|
Sermorelin acetate |
developmental |
--- |
August 20, 1999 |
|
Sodium
dimethyldithiocarbamate |
developmental |
128041 |
March 30 1999 |
|
Sodium fluoroacetate |
male |
62748 |
November 6, 1998 |
|
Streptomycin sulfate |
developmental |
3810740 |
January 1, 1991 |
Streptozocin
(streptozotocin)
|
developmental,
female, male
|
18883664
|
August
20, 1999
|
|
Sulfasalazine |
male |
599791 |
January 29, 1999 |
|
Sulindac |
developmental, female |
38194502 |
January 29, 1999 |
|
|
|
|
|
|
Tamoxifen citrate |
developmental |
54965241 |
July 1, 1990 |
|
Temazepam |
developmental |
846504 |
April 1, 1990 |
|
Teniposide |
developmental |
29767202 |
September 1, 1996 |
|
Terbacil |
developmental |
5902512 |
May 18, 1999 |
|
Testosterone cypionate |
developmental |
58208 |
October 1, 1991 |
|
Testosterone enanthate |
developmental |
315377 |
April 1, 1990 |
|
2,3,7,8-Tetrachlorodibenzo-para-dioxin (TCDD) |
developmental |
1746016 |
April 1, 1991 |
|
Tetracycline (internal
use) |
developmental |
60548 |
October 1, 1991 |
|
Tetracyclines (internal use)
|
developmental |
--- |
October 1, 1992 |
|
Tetracycline hydrochloride |
developmental |
64755 |
January 1, 1991 |
|
(internal use) |
|
|
|
|
Thalidomide |
developmental |
50351 |
July 1, 1987 |
|
Thioguanine |
developmental |
154427 |
July 1, 1990 |
|
Thiophanate methyl |
female, male |
23564058 |
May 18, 1999 |
|
Tobacco smoke (primary) |
developmental, female,
male |
--- |
April 1, 1988 |
|
Tobramycin sulfate |
developmental |
49842071 |
July 1, 1990 |
|
Toluene |
developmental |
108883 |
January 1, 1991 |
|
Triadimefon |
developmental, female,
male |
43121433 |
March 30, 1999 |
|
Triazolam |
developmental |
28911015 |
April 1, 1990 |
Tributyltin
methacrylate
|
developmental
|
2155706
|
December
1, 1999
|
Trientine
hydrochloride
|
developmental
|
38260014
|
February
27, 2001
|
Triforine
|
developmental
|
26644462 |
June
18, 1999
|
|
Trilostane |
developmental |
13647353 |
April 1, 1990 |
|
Trimethadione |
developmental |
127480 |
January 1, 1991 |
|
Trimetrexate glucuronate |
developmental |
82952645 |
August 26, 1997 |
|
Triphenyltin hydroxide |
developmental |
76879 |
March 18, 2002 |
|
|
|
|
|
|
Uracil mustard |
developmental, female,
male |
66751 |
January 1, 1992 |
|
Urethane |
developmental |
51796 |
October 1, 1994 |
|
Urofollitropin |
developmental |
97048130 |
April 1, 1990 |
|
|
|
|
|
|
Valproate (Valproic acid) |
developmental |
99661 |
July 1, 1987 |
|
Vinblastine sulfate |
developmental |
143679 |
July 1, 1990 |
|
Vinclozolin |
developmental |
50471448 |
May 15, 1998 |
|
Vincristine sulfate |
developmental |
2068782 |
July 1, 1990 |
|
|
|
|
|
|
Warfarin |
developmental |
81812 |
July 1, 1987 |
|
|
|
|
|
Zileuton
|
developmental, female
|
111406872
|
December 22, 2000
|
Date:
November 14, 2003