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The Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65
or the Act) requires the Governor to publish, and update at least
annually, a list of chemicals known to the State to cause cancer
or reproductive toxicity. The Act provides two mechanisms for administratively
listing chemicals as known to the State to cause cancer or reproductive
toxicity [Health and Safety Code Section 25249.8(b)]. One mechanism
by which a chemical is listed is if a state or federal agency has
formally required that the chemical be labeled or identified as
causing cancer or reproductive toxicity. The criteria for listing
chemicals through this mechanism are set forth in Title 22,
California Code of Regulations (22 CCR) Section 12902. The
second mechanism for administrative listing, and the subject of
todays notice, is if a body considered to be authoritative
by the states qualified experts has formally identified it
as causing cancer or reproductive toxicity. The United States Environmental
Protection Agency (US EPA) has been identified as an authoritative
body for purpose of the Act.
As the lead agency for the implementation of Proposition 65, the
Office of Environmental Health Hazard Assessment (OEHHA) of the
California Environmental Protection Agency is investigating the
possible listing of the chemicals identified below, based upon information
in the references cited. All of the chemicals listed below are proposed
for administrative listing based upon the US EPA having identified
them as causing developmental and reproductive toxicity. Documentation
summarizing the rationale for considering the evaluation of these
chemicals for possible administrative listing is available from
OEHHAs Proposition 65 Implementation Office at the address
and telephone number indicated below, or from the Internet at the
following address: http://www.oehha.ca.gov.
Download the documentation
in Adobe Acrobat PDF format.
OEHHA is committed to public participation and external scientific
peer review in its implementation of Proposition 65, and welcomes
public input on this listing process. As part of its efforts to
ensure that regulatory decisions are based upon a thorough consideration
of all relevant information, OEHHA is soliciting information which
may be relevant to the evaluation of these chemicals in the context
of the Proposition 65 authoritative body listing criteria (22 CCR Section 12306).
A public forum will be held on November 20th, 1998,
to provide an opportunity for interested parties to present oral
comments and to discuss the scientific data and other information
relevant to a determination as to whether these chemicals meet the
criteria for listing set forth in 22 CCR Section 12306. The
public forum will be conducted at 10:00 a.m. in the Auditorium
at 714 P St., Sacramento, California, and will last until all business
has been conducted or until 5:00 p.m.
Written comments provided in triplicate, along with supporting
information, may also be submitted to:
Cynthia Oshita
Office of Environmental Health Hazard Assessment
1001 I Street,
Sacramento, CA 95814
FAX: (916) 327-1097
Telephone: (916) 445-6900
In order to be considered, comments must be postmarked (if sent
by mail) or received at OEHHA (if hand-delivered or sent by fax)
by December 8, 1998.
Following the review of all comments received, OEHHA will announce
its intention to proceed with the listing of those candidate chemicals
that meet the regulatory criteria for administrative listing in
a Notice of Intent to List Chemicals.
Chemicals which may meet the criteria set forth in 22 CCR Section 12306
for listing as known to cause reproductive toxicity via the "authoritative
bodies" mechanism:
| Chemical |
CAS No. |
Reproductive Endpoint |
Referencea |
| Avermectin B1 (abermectin) |
71751-41-2
65195-55-3
65195-56-3 |
Development |
US EPA (1994a,b, 1996) |
| delta-8,9-isomer of Avermectin
B1 |
--- |
Development |
US EPA (1996) |
| Nitrapyrin |
1929-82-4 |
Development |
US EPA (1994a,b) |
| Thiabendazole |
148-79-9 |
Development |
US EPA (1994a,b) |
| Triadimefon |
43121-43-4 |
Development Male reproductiveFemale
reproductive |
US EPA (1994a,b) |
| Triphenyltin hydroxide |
76-87-9 |
Development |
US EPA (1994a,b) |
a Formal identification by US EPA of chemicals causing
reproductive toxicity is provided in US EPA (1994b) below, while
additional information on the basis for such identification is
provided in US EPA (1994a).
References
US Environmental Protection Agency (US EPA, 1994a). Proposed Rule:
Addition of Certain Chemicals; Toxic Chemical Release Reporting;
Community Right to Know. Federal Register (59 FR 1788).
US Environmental Protection Agency (US EPA, 1994b). Final Rule:
Addition of Certain Chemicals; Toxic Chemical Release Reporting;
Community Right to Know. Federal Register (59 FR 61432).
US Environmental Protection Agency (US EPA, 1996). Pesticide Tolerance;
Avermectin B1 and Its Delta-8,9-Isomer. Final Rule. Federal Register
Vol. 61, No. 47, pages 9350-9352.
You will need the free program Adobe Acrobat Reader to view or
print PDF files 
For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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