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The Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65)
provides two mechanisms for administratively listing chemicals which
are known to the State to cause cancer or reproductive toxicity
(Health and Safety Code Section 25249.8(b)). One such mechanism
by which a chemical may be listed is if a body considered to be
authoritative by the states qualified experts has formally
identified it as causing cancer or reproductive toxicity. The following
are identified as authoritative bodies for purposes of Proposition
65 as it pertains to chemicals known to cause reproductive toxicity:
the US Environmental Protection Agency (US EPA), the International
Agency for Research on Cancer (for transplacental carcinogenicity
only), the US Food and Drug Administration, and the National Institute
for Occupational Safety and Health. The criteria for listing chemicals
through the authoritative bodies mechanism are set forth in Title 22,
California Code of Regulations (22 CCR), Section 12306.
As the lead agency for the implementation of Proposition 65, the
Office of Environmental Health Hazard Assessment (OEHHA) of the
California Environmental Protection Agency intends to list the chemicals
identified below as known to the State to cause reproductive toxicity,
pursuant to this administrative mechanism as provided in Health
and Safety Code Section 25249.8(b) and 22 CCR, Section 12306.
Relevant information on three of the chemicals in todays
notice, chlorsulfuron, ethyl dipropylthiocarbamate, and quizalofop-ethyl,
was requested in a notice published in the California
Regulatory Notice Register on October 30, 1998. A similar notice
was published on the other 2 chemicals included in todays
on November 20, 1998.
Public forums were held on December 18, 1998, and January 11, 1999,
respectively. Public comments were received on three of these chemicals,
chlorsulfuron, ethyl dipropylthiocarbamate, and quizalofop-ethyl.
OEHHA has completed its review of the comments and has determined
the chemicals meet the criteria for listing under 22 CCR, Section 12306.
OEHHA is issuing this notice of intent to list for the chemicals
identified in the table below. A document providing more detail
on the basis for the listing can be obtained from OEHHAs Proposition 65
Implementation Office at the address and telephone number indicated
below, or by downloading the document from this site.
Download the document as an
Adobe Acrobat PDF file.
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Anyone objecting to the listing of the chemicals identified below
as causing reproductive toxicity on the basis that there is no substantial
evidence that the criteria of sufficiency of evidence of reproductive
toxicity identified in 22 CCR, Section 12306 have been satisfied
should provide written comments in triplicate, along with supporting
documentation, by mail or by fax to:
Ms. Cynthia Oshita
Office of Environmental Health Hazard Assessment
Post Office Box 4010
Sacramento, CA 95812-4010
Fax No.: (916) 327-1097
Telephone: (916) 445-6900
Comments may also be hand-delivered to Ms. Oshita at the Office
of Environmental Health Hazard Assessment at the same address.
In order to be considered, comments must be postmarked (if sent
by mail) or received at OEHHA (if delivered in person or sent by
FAX) by 5:00 p.m. on Monday, March 29, 1999.
The following chemicals have been determined by OEHHA to meet the
criteria set forth in 22 CCR, Section 12306 for listing as
causing reproductive toxicity under the authoritative bodies mechanism:
|
Chemical
|
CAS No.
|
Toxicological Endpoint |
Referencea
|
| Chlorsulfuron |
6490-27-23
|
developmental toxicity
female reproductive toxicity
male reproductive toxicity |
US EPA (1994a,b) |
| Ethyl dipropyl-thiocarbamate |
759-94-4
|
developmental toxicity |
US EPA (1994a,b) |
| Quizalofop-ethyl |
76578-14-8
|
male reproductive
toxicity |
US EPA (1994a,b) |
| Dichlorophene |
97-23-4
|
developmental toxicity |
US EPA (1994a,b) |
| 2,4-DP (dichloroprop) |
120-36-5
|
developmental toxicity |
US EPA (1994a,b) |
a Formal identification by US EPA of chemicals causing
reproductive toxicity is provided in US EPA (1994b) below, while
additional information on the basis for such identification is provided
in US EPA (1994a).
References
US Environmental Protection Agency (US EPA, 1994a) Proposed Rule:
Addition of Certain Chemicals; Toxic Chemical Release Reporting;
Community Right to Know. Federal Register (59 FR 1788).
US Environmental Protection Agency (US EPA, 1994b). Final Rule:
Addition of Certain Chemicals; Toxic Chemical Release Reporting;
Community Right to Know. Federal Register (59 FR 61432).
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For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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