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Air Toxicology and Epidemiology

Hot Spots Guidelines

• Non-cancer health effects (RELs)
• Cancer Potency Factors
• Exposure Assessment and Stochastic
• Risk Assessment Methodology
• Proposed Reference Exposure Levels for Benzene
  [01/22/14]
• Notice of Adoption of Reference Exposure Levels for Caprolactam
  [10/18/13]
• Notice of Adoption of Revised Reference Exposure Levels for 1,3-Butadiene
  [07/26/13]
• Notice of Public Comment Period and Workshops on Proposed Revised Reference Exposure Levels for Benzene
  [06/21/13]
• Revised Proposed Reference Exposure Levels for 1,3-butadiene
  [03/01/13]
• Proposed Reference Exposure Levels for 1,3-butadiene
  [09/11/12]
• Notice of Adoption of Air Toxics Hot Spots Program Risk Assessment Guidelines: Revised Technical Support Document for Exposure Assessment And Stochastic Analysis
  [08/27/12]
• Air Toxics Hot Spots Program Risk Assessment Guidelines: Technical Support Document for Exposure Assessment and Stochastic Analysis, June 2012
  [06/21/12]
• Notice of Public Comment Period on Proposed Revised Reference Exposure Levels for 1,3-Butadiene
  [05/18/12]
• Notice of Adoption of Revised Reference Exposure Levels For Nickel And Nickel Compounds
  [03/23/12]
• Air Toxics Hot Spots Risk Assessment Guidelines Technical Support Document for Exposure Assessment and Stochastic Analysis, February 2012
  [03/09/12]
• Public comment period on  the updated draft of the Air Toxics Hot Spots Program Technical Support Document For Exposure Assessment and Stochastic Analysis has been extended to January 13, 2012.
  [01/06/12]
• Proposed Revisions to the Technical Support Document for Exposure Assessment and Stochastic Analysis
  [12/16/11]
• Proposed Revisions To The Technical Support Document For Exposure Assessment And Stochastic Analysis
  [11/07/11]
• Proposed Reference Exposure Levels for Caprolactam and Nickel
  [04/01/11]
• Adoption of Revised Toxicity Equivalency Factors for (TEF_WHO-05) for PCDDs, PCDFs, and Dioxinlike PCBs
  [01/31/11]
• Materials for Consideration by the Scientific Review Panel at Their Next Meeting (January 21, 2011) [12/27/10]
  • Proposed Revisions to the Technical Support Document for Cancer Potency Factors, Appendix C - Use of the Toxicity Equivalency Factor (TEFWHO 97 and TEFWHO 05) Scheme for Estimating Toxicity of Mixtures of Dioxin-Like Chemicals
  • Proposed Reference Exposure Levels for Caprolactam
• Proposed Revised Reference Exposure Levels For Toluene Diisocyanate And Methylene Diphenyl Diisocyanate
  [06/17/10]
• Proposed Revised Reference Exposure Levels For Nickel And Nickel Compounds
  [06/04/10]
• Proposed Reference Exposure Levels For Methylene Diphenyl Diisocyanate, Toluene Diisocyanate And Caprolactam: Announcement Of Public Workshops
  [06/02/10]
• Proposed Reference Exposure Levels for Caprolactam
  [05/20/10]
• Proposed Revised Reference Exposure Levels For Toluene Diisocyanate And Methylene Diphenyl Diisocyanate
  [04/23/10]
• Proposed Revisions to the Technical Support Document for Cancer Potency Factors, Appendix C - Use of the Toxicity Equivalency Factor (TEF_{WHO 97} and TEF_{WHO 05}) Scheme for Estimating Toxicity of Mixtures of Dioxin-Like Chemicals
  [08/07/09]
• Adoption of the Revised Air Toxics Hot Spots Program Technical Support Document for Cancer Potency Factors
  [06/01/09]
• Meeting of the Scientific Review Panel for Toxic Air Contaminants on May 12, 2009.
  [04/29/09]
• Adoption of the Revised Air Toxics Hot Spots Program Technical Support Document for the Derivation of Noncancer Reference Exposure Levels and RELs for Six Chemicals
  [12/19/08]
• Meeting of the Scientific Review Panel for Toxic Air Contaminants on December 5, 2008
  [11/25/08]
  • Continuation of the Panel’s review of the draft Reference Exposure Levels for acrolein, acetaldehyde, arsenic, formaldehyde, manganese and mercury. (December 2008)
  • Continuation of the Panel’s review of the draft report “Air Toxics Hot Spots Risk Assessment Guidelines Part II: Technical Support Document for Cancer Potency Factors” (December 2008)
• Meeting of the Scientific Review Panel for Toxic Air Contaminants on October 30, 2008
  [10/10/08]
  • Continuation of the Panel’s review of the draft Reference Exposure Levels for acrolein, acetaldehyde, arsenic, mercury, manganese, and formaldehyde (September 2008)
  • Review of the draft report “Air Toxics Hot Spots Risk Assessment Guidelines Part II: Technical Support Document for Cancer Potency Factors” (October 2008)
• Air Toxics Hot Spots Program, Revisions to the Technical Support Document for Noncancer Risk Assessment
  [07/18/08]
• Notice to interested parties: Notice of public comment period on Air Toxics Hot Spots Program, Proposed Revisions to the Technical Support Document for Cancer Potency Factors
  [6/20/08]
• Proposed Revisions to the Technical Support Document for Noncancer Risk Assessment
  [06/13/08] - 3rd revision
• Proposed Revisions to the Technical Support Document for Noncancer Risk Assessment
  [4/24/08] - 2nd revision
• Extension of the Public Comment Period for Air Toxics Hot Spots Program Proposed Revisions to the Technical Support Document for Noncancer Risk Assessment
  [12/19/07]
• Adoption of a Unit Risk Value for Ethylbenzene
  [11/14/07]
• Notice to interested parties: Notice of public comment period on Air Toxics Hot Spots Program, Proposed Revisions to the Technical Support Document for Noncancer Risk Assessment - comment period extended
  [11/02/07]
• Notice to Interested Parties Proposal for the Adoption of a Unit Risk Factor for Ethylbenzene
  [08/27/07]
• Notice to Interested Parties Notice of Public Comment Period on Toxic Air Contaminants Program – Proposal for the Adoption of a Unit Risk Factor for Ethylbenzene
  [04/20/07]
• Document Available: Technical Support Document for Describing Available Cancer Potency Factors, May 2005
  [05/31/05]
• Document Available: Draft Chronic Reference exposure for Silica (Crystalline, respirable), and OEHHA's responses to public comments
  [11/03/04]
• Adoption of a Unit Risk Value for Naphthalene
  [08/03/04]
• Adoption of Air Toxics Hot Spots Program Guidance Manual for Preparation of Health Risk Assessments
  [10/03/03]
• Adoption of the Revised Toxicity Equivalency Factors (TEF _WHO-97) for PCDDs, PCDFs, and Dioxin-Like PCBs
  [08/29/03]
• Notice of Public Comment Period on Air Toxics Hot Spots Program - Chronic Toxicity Summary Silica (Crystalline, Respirable)
  [04/25/03]
• Air Toxics Hot Spots Updated Program Risk Assessment Guidelines, Part II: Technical Support Document for Using Cancer Potency Factors
  [12/19/02]
  • Download Part II
• Notice to Interested Parties Air Toxics Hot Spots Program Guidance Manual for Preparation of Health Risk Assessments: Draft for Public Comment
  [06/06/02]
• Adoption of Chronic Reference Exposure Levels (RELs) for Airborne Toxicants
  [12/28/01]
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part III. The Determination of Chronic Reference Exposure Levels - 22 Chemicals
  [01/22/01]
  • Download the 22 chemical summaries
• Notice to Interested Parties Air Toxics Hot Spots Program Risk Assessment Guidelines. Part IV. Exposure Assessment and Stochastic Technical Support Document
  [10/27/00]
  • Download Part IV
• Notice of Public Comment Period on Air Toxics "Hot Spots" Program Risk Assessment Guidelines
  [07/21/00]
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part III. The Determination of Chronic Reference Exposure Levels for Airborne Toxicants - 16 Chemicals
  [05/02/00]
  • Download the 16 Chemical Summaries
• Notice to Interested Parties Draft Air Toxics Hot Spots Program Risk Assessment Guidelines. Part IV. Exposure Assessment and Stochastic Technical Support Document - comment period closed
  [03/10/00]
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part III. The Determination of Chronic Reference Exposure Levels for Airborne Toxicants. 22 Chemicals
  [02/23/00]
  • Download Risk Assessment Guidelines, Part III
• Notice to Interested Parties Notice of Public Comment Period on Air Toxics "Hot Spots" Program Risk Assessment Guidelines - 2nd Set of 40 Chronic RELs - Comment Period Closed (10/27/99)
  [09/27/99]
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part III. The Determination of Noncancer Chronic Reference Exposure Levels for Airborne Toxicants (22 chemicals) and OEHHA's Responses to Public Comments. - Revised DRAFT
  [06/11/99]
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part II. Technical Support Document for Describing Available Cancer Potency Factors
  [04/20/99]
  • Download Risk Assessment Guidelines, Part II
• Air Toxics Hot Spots Program Risk Assessment Guidelines Part I. Technical Support Document for The Determination of Acute Reference Exposure Levels for Airborne Toxicants.
  [04/05/99]
  • Download Risk Assessment Guidelines, Part I
• Response to Comments on the Scientific Review Panel Draft of the Air Toxic Hot Spots Risk Assessment Guidelines Part 1: Determination of Acute Reference Exposure Levels for Airborne Toxicants (received by OEHHA Jan. 18, 1999)
  [03/01/99]
• Response to Comments on the Scientific Review Panel Draft of the Air Toxic Hot Spots Risk Assessment Guidelines Part 1: Determination of Acute Reference Exposure Levels for Airborne Toxicants (November 1998)
  [02/04/99]
• Notice to Interested Parties Notice of Public Comment Period on Air Toxic "Hot Spots" Program Risk Assessment Guidelines, Part II: Technical Support Document for the Determination of Acute Reference Exposure Levels for Airborne Toxicants. - Comment Period Closed (11/30/1998)
  [10/30/98]
• Notice to Interested Parties Notice of Extension of Public Comment Period for Air Toxics "Hot Spots" Guidelines Part III: Technical Support Document for Determining Chronic Reference Exposure Levels - Comment Period Closed (01/29/98)
  [12/26/97]
• Responses to Comments by the Staff of the Office of Environmental Health Hazard Assessment (OEHHA) on the April 1994, Draft Technical Support Document for Using Cancer Potency Factors.
  [12/05/97]
• Notice to Interested Parties October 31, 1997 Notice of Public Comment Period and Notice of Public Workshops on Air Toxic "Hot Spots" Program Risk Assessment Guidelines, Part III: Technical Support Document for the Determination of Noncancer Chronic Reference Exposure Levels - Comment Period Closed (12/30/97)
  [10/01/97]
• Notice to Interested Parties October 31, 1997 Notice of Public Comment Period on Air Toxics "Hot Spots" Program Risk Assessment Guidelines for Determining Cancer Potency Factors - Comment Period Closed (12/30/97)
  [10/01/97]